Value of Additional Corpus Biopsy for Diagnosis of H Pylori in Atrophic Gastritis. Prospective Non-randomized Study
- Conditions
- Helicobacter PyloriCORPUS BIOPSIESGastric Antrum
- Interventions
- Other: ENDOSCOPIC GASTRIC BIOPSIES FROM ANTRUM AND BODY
- Registration Number
- NCT02675010
- Lead Sponsor
- Mansoura University
- Brief Summary
There are controversies about the best sites -biopsy based -tests for H pylori associated gastritis. The study is designed to evaluate the optimal site of gastric mucosal biopsy for identification of Helicobacter pylori, especially in case of gastric atrophy and/or intestinal metaplasia.
- Detailed Description
. The study is designed to evaluate the optimal site of gastric mucosal biopsy for identification of Helicobacter pylori, especially in case of gastric atrophy and/or intestinal metaplasia. 400 patients with dyspepsia are planned to be enrolled in this study. in addition to the routine antral biospy, corpus biospies are taken to evaluate the optimal site of gastric mucosal biopsy for identification of Helicobacter pylori, especially in case of gastric atrophy and/or intestinal metaplasia.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 400
- Patients included in this study are those with peptic ulcer disease, previous upper gastrointestinal surgery, a known or a suspected past history of H.pylori eradication therapy, a personal or first-degree family history of gastric cancer
- those having received antibiotic or proton pump inhibitor treatment one month beforehand
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description ENDOSCOPIC GASTRIC BIOPSIES ENDOSCOPIC GASTRIC BIOPSIES FROM ANTRUM AND BODY ENDOSCOPIC BIOPSEIS TAKEN FROM BOTH ANTRUM AND CORPUS FOR H PYLORI DETECTION
- Primary Outcome Measures
Name Time Method H PYLORI POSITIVITY 2 YEARS
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Mansoura University Hospital
🇪🇬Mansoura, Egypt