NCT00824226已完成不适用
Effect of Magnesium Treatment on Plasma Calcium in Hypoparathyroid Patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Calcium level at the end of magnesium treatment compared to pretreatment level
研究概览
简要总结
Study hypothesis: supplementary magnesium may influence the blood calcium level in treated hypoparathyroid patients. Patients will be treated with supplementary magnesium (350 mg/day) for 3 weeks. Calcium and other relevant blood parameters will be measured before the treatment, at the end of treatment and 2 weeks after stopping treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •primary or secondary hypoparathyroidism
- •treatment with calcium plus vitamin D analogue
- •ionized calcium 1,0-1,29 mmol/L
- •magnesium level 0,7-1,05 mmol/L
- •TSH 0.1- 10 imU/L
排除标准
- •any other disease known to influence plasma Ca level
- •pregnancy
- •creatinine > 150 microM/L
- •patient has used supplementary magnesium within 2 previous months
结局指标
主要结局
Calcium level at the end of magnesium treatment compared to pretreatment level
时间窗: 3 weeks
次要结局
- Calcium level after stopping treatment compared to the level at the end of magnesium treatment(2 weeks)
研究者
研究点 (2)
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