An Experimental, Randomized Trial Comparing Mindfulness Meditation Versus Clinical Hypnosis for Acute Pain: a Test of Effects and Mechanisms
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Mindfulness Meditation
- Sponsor
- The University of Queensland
- Enrollment
- 105
- Locations
- 1
- Primary Endpoint
- Pain unpleasantness
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
This trial aims to determine the effects and mechanisms (mediators and moderators) of brief training in mindfulness meditation versus clinical hypnosis on acute, experimental pain.
Detailed Description
Participants (N=200 with complete data) will be healthy undergraduate students or community-based individuals. An experimental, randomised trial will be implemented, with participants randomly assigned to either five daily, 20-minute mindfulness meditation sessions or clinical hypnosis sessions. Repeated measures and experimental pain manipulation will be implemented. Aim 1 is to examine the effects of these two treatments on experimental pain outcomes. Aim 2 is to examine the moderators of these effects. Aim 3 is to determine the mediators underlying improved experimental pain outcomes. Results will refine theory and will inform the future streamlining of treatments to target those mechanisms shown to be of most critical importance.
Investigators
Eligibility Criteria
Inclusion Criteria
- •18 years of age or older;
- •Able to read, speak and understand English.
Exclusion Criteria
- •Pregnancy, heart or vascular disease, Raynaud's disease, sickle cell disease, seizure disorder, high blood pressure, or diabetes;
- •Experience of recurrent fainting spells;
- •Report of a chronic pain condition;
- •Use of alcohol and/or pain medication in the last 24-hours;
- •Currently receiving psychiatric care;
- •Problems with allergic skin reactions or excessive bruising;
- •Previous participation in a cold pressor experiment.
- •All participants will be asked to consume a fruit box drink prior to the cold pressor to prevent vasovagal reactions.
- •These exclusion criteria are standard when using a cold pressor task in a healthy undergraduate population and ensure safe procedures to mitigate any potential risks.
Outcomes
Primary Outcomes
Pain unpleasantness
Time Frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
Numerical rating scale in response to exposure to a cold pressor task.
Pain intensity
Time Frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
Numerical rating scale in response to exposure to a cold pressor task.
Pain tolerance
Time Frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
How long (in seconds) participants tolerate the cold pressor task with the time starting at the point of immersion and stopping when the hand, wrist and forearm were withdrawn from the refrigerated water.
Secondary Outcomes
- Mechanism: Attention Network Task(Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5))
- Mechanism: Mindfulness(Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5))
- Physiological response to pain stimulus(Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5))
- Mechanism: Mind Wandering Task(Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5))
- Mechanism: Pain appraisals(Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5))
- Mechanism: Hypnotizability(Baseline score at Experimental Session 1 (Day 1))
- Mechanism: Pain catastrophizing(Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5))
- Mechanism: Pain-Related Cognitive Processes(Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5))
- Mechanism: Pre-treatment expectancies(Baseline score at Experimental Session 1 (Day 1))