ISRCTN17414946已完成1 期
A pilot study to evaluate the safety and efficacy of interferon beta-1a (IFN ß-1a) in the treatment of patients presenting with Ebola virus illness
Sustainable health Foundation (FOSAD) & Center of Excellence for Training on Research and Priority Diseases (CEFORPAG)0 个研究点目标入组 50 人开始时间: 2016年7月19日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 50
研究概览
简要总结
2017 results in https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321269/ (added 01/03/2019)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Able to provide informed consent (ubstitute decision maker may provide informed consent in cases where the patient is ill and unable to provide informed consent)
- •2. Aged between 18 and 70 years on the day of inclusion
- •3. In the treatment centre
- •4. Confirmed ebola virus infection by RT-PCR
- •5. Symptom onset < 6 days
- •6. Able to comply with trial procedures
排除标准
- •1. Known hypersensitivity to IFN ß preparations
- •2. Pregnancy
- •3. Chronic liver disease with synthetic dysfunction and/or decompensation, history of bleeding
- •4. Moderate to severe congestive heart failure - grade III or IV left ventricular function
- •5. Previous history of serious psychiatric illness
- •6. History of sever or active autoimmune disease
研究者
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