Study of Myocardial Recovery after Exercise Training in Heart Failure

Phase 2

Withdrawn

• Conditions: decompensation; heartfailure; 10019280

• Registration Number: NL-OMON33053
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

- congestive heart failure
- LVEF < 35%
- NYHA class II-III
- minimum 3 months of optimal medical treatment

Exclusion Criteria

- significant intercurrent illness last 6 weeks
- known severe ventricular arrhythmia
- significant ischemia
- other heart disease that limits exercise tolerance

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Evaluation criteria are cardiac volumes and function, aerobic capacity, quality<br /><br>of life, and level of physical activity, assessed before and after the training<br /><br>program, and at follow-up one year after start of training. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Safety assesment of interval training in heartfailure.<br /><br>To determine whether beneficial effects of training are sustainable for longer<br /><br>periods of time.<br /><br>To assess whether AIT may reduce the incidence of serious adverse events, such<br /><br>as worsening of heart failure requiring intensified diuretic treatment, death<br /><br>or hospitalization due to cardiovascular disease within one year follow-up.</p><br>