Effects of exercise training on cardiac autonomic function in patients with subclinical diabetic heart disease

Not Applicable

Recruiting

• Conditions: Diabetic Cardiomyopathy; Cardiovascular - Other cardiovascular diseases; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12609000950268
• Lead Sponsor: The University of Queensland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-11-04
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 225

Inclusion Criteria

Type 2 diabetes mellitus

Exclusion Criteria

Known cardiovascular disease, pregnancy or breast-feeding, psychiatric illness precluding compliance, atrial fibrillation, other serious medical illness including renal impairment

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in heart rate variability following exercise training.<br><br>Heart rate variability will be assessed by the coefficient of variation of R-R intervals recorded over 5 minutes using an electrocardiogram (ECG).[Patients will be tested for heart rate variability pre and post a 6-month exercise training intervention.];Improvement in exercise capacity (maximal oxygen uptake - VO2max) following exercise training.[Patients will perform maximal treadmill exercise testing for maximal oxygen uptake (VO2max) pre and post a 6-month exercise training intervention.<br><br>Note: Heart rate variability and exercise capacity, comprising the two primary endpoints, will each be reported fully and with equal emphasis.]