Role of urea and ureolytic bacteria in dental calculus
- Registration Number
- CTRI/2018/08/015429
- Lead Sponsor
- iberia Libertina Dsouza
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 135
1.Subjects having a minimum of 24 natural teeth
excluding the third molars
2.Presence of dental calculus on the surfaces of
the teeth
3.Subjects should be systemically healthy
4.No history of periodontal treatment in the
last 6 months
5.Control subjects will be age and gender
matched to test group subjects
1.Patients with a history of any systemic
disease (Diabetes mellitus, hypertension,
liver disease, kidney disease )
2.Patients with a history of antibiotic, anti-
inflammatory or immunosuppressive drug
therapy 6 month prior to the study.
3.Patients with history of any salivary gland
diseases
4.Patients with any apparent oral infections
(i.e. herpes or candidiasis )
5.Patients with a history of radiation therapy.
6.Pregnant and lactating women.
7.Patients who are chronic smokers, tobacco
users and alcohol users.
8.Denture wearers.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To measure levels of salivary urea, evaluate the presence and quantify the amount of ureolytic bacteria within dental calculus using gram staining, bacterial culture, biochemical reactions and to determine a possible correlation between salivary urea and ureolytic bacteria in dental calculus in patients with good, fair and poor oral hygiene.Timepoint: Within 24 hours
- Secondary Outcome Measures
Name Time Method To evaluate the periodontal status using gingival index, clinical attachment loss , pocket probing depth and to determine a possible correlation between salivary urea and periodontal status in patients with good, fair and poor oral hygiene.Timepoint: Within 24 hours