Prospective Study of Sudden Deafness
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Audiometry
研究概览
简要总结
To study the effective treatment of sudden deafness by giving prednisone, hyperbaric oxygen and somatosensory stimulation to sudden deafness patients.
详细描述
60 cases of sudden deafness within 2 months of 14-80 years old were randomly divided into two groups. They underwent hearing tests, magnetic resonance imaging of the head, and routine hospital admissions. One group was given prednisone for 1 mg / kg body weight × 7 days + somatosensory stimulation × 30 days, the other group was given prednisone for 1 mg / kg body weight × 7 days + hyperbaric oxygen × 15 days, and repeated electrical audiometry every week. One month and three months after the experiment, repeated audiometry.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 14 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Sudden deafness
- •History within 2 months
- •Age 14-80
排除标准
- •Neurological diseases (such as brain tumors)
- •Patients with mental / mental illness undergoing treatment
- •Pregnant women and patients with other untreatable diseases
- •Finding the cause of sensorineural deafness
- •Patients Not Suitable for Hyperbaric Oxygen
- •A patient with dermatosis
结局指标
主要结局
Audiometry
时间窗: Three months from the patient's selection to the end of treatment
Evaluate the patient's hearing to determine whether it has improved.
Cranial magnetic resonance imaging
时间窗: When patients are enrolled
Judging whether the patient's inner ear has pathological changes or not
次要结局
未报告次要终点
研究者
Dan Su
principal investigator
The First Affiliated Hospital of Anhui Medical University