Prospective Study of Sudden Deafness
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Audiometry
Study Overview
Brief Summary
To study the effective treatment of sudden deafness by giving prednisone, hyperbaric oxygen and somatosensory stimulation to sudden deafness patients.
Detailed Description
60 cases of sudden deafness within 2 months of 14-80 years old were randomly divided into two groups. They underwent hearing tests, magnetic resonance imaging of the head, and routine hospital admissions. One group was given prednisone for 1 mg / kg body weight × 7 days + somatosensory stimulation × 30 days, the other group was given prednisone for 1 mg / kg body weight × 7 days + hyperbaric oxygen × 15 days, and repeated electrical audiometry every week. One month and three months after the experiment, repeated audiometry.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Care Provider)
Eligibility Criteria
- Ages
- 14 Years to 80 Years (Child, Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Sudden deafness
- •History within 2 months
- •Age 14-80
Exclusion Criteria
- •Neurological diseases (such as brain tumors)
- •Patients with mental / mental illness undergoing treatment
- •Pregnant women and patients with other untreatable diseases
- •Finding the cause of sensorineural deafness
- •Patients Not Suitable for Hyperbaric Oxygen
- •A patient with dermatosis
Outcomes
Primary Outcomes
Audiometry
Time Frame: Three months from the patient's selection to the end of treatment
Evaluate the patient's hearing to determine whether it has improved.
Cranial magnetic resonance imaging
Time Frame: When patients are enrolled
Judging whether the patient's inner ear has pathological changes or not
Secondary Outcomes
No secondary outcomes reported
Investigators
Dan Su
principal investigator
The First Affiliated Hospital of Anhui Medical University