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Clinical Trials/NCT04860206
NCT04860206
Completed
Not Applicable

Vpliv COVID19 na Izgubo Funkcionalnih zmožnosti Pacientov po zaključenem bolnišničnem Zdravljenju The Effect of COVID19 on the Loss of Functional Capacity of Patients After Hospitalization

Science and Research Centre Koper1 site in 1 country43 target enrollmentJanuary 5, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Covid19
Sponsor
Science and Research Centre Koper
Enrollment
43
Locations
1
Primary Endpoint
Pulse wave velocity (PWV)
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The main objective of the proposed study is to evaluate the impact of coronavirus (2019-nCoV), hereafter COVID -19, on patients' loss of functional capacity after completion of hospital treatment. Specifically, the research will focus on examining changes in musculoskeletal, cardiovascular, and respiratory function, as well as motor control. In addition, we aim to evaluate rehabilitation treatments after recovery from COVID -19 and consider additional preventive measures based on previous experience.

Detailed Description

The combination of such a severe respiratory disease as COVID -19 with motor inactivity could have very serious consequences for a person's general health even after COVID -19 symptoms have subsided. To date, the effects of COVID -19 on individual muscle status have not been extensively studied. Therefore, the main objective of this study will be to evaluate the muscle status of patients after COVID -19. In addition, we will be interested in longitudinal monitoring of individuals' rehabilitation, where they will receive instructions based on measured outcomes at hospital discharge. We will also be interested in considering additional preventive measures for future patients based on previous experience of infected and hospitalized COVID -19 patients.

Registry
clinicaltrials.gov
Start Date
January 5, 2021
End Date
September 30, 2021
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Science and Research Centre Koper
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Completed hospital treatment after a positive COVID-19 test
  • Signed written consent

Exclusion Criteria

  • Still testing positive for COVID -19 at discharge.
  • Severe musculoskeletal injuries (e.g., disability).
  • Inability to follow instructions when performing the test.

Outcomes

Primary Outcomes

Pulse wave velocity (PWV)

Time Frame: Change in PWV between both assessment points (pre- to 2 months post-measurement)

Measuring endothelium function in supine

Spirometry

Time Frame: Change in FVC (%) between both assessment points (pre- to 2 months post-measurement)

Measurement of lung function, specifically the forced vital capacity (FVC)

Timed up and go test (TUG)

Time Frame: Change in time on TUG between both assessment points (pre- to 2 months post-measurement)

Functional performance of the patients from sitting to standing, walking and turning

Secondary Outcomes

  • Trail making test B(Change in time to solve the TMT B test between both assessment points (pre- to 2 months post-measurement))
  • Walking velocity(Change in gait velocity between both assessment points (pre- to 2 months post-measurement))

Study Sites (1)

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