跳至主要内容
临床试验/CTRI/2019/07/020470
CTRI/2019/07/020470尚未招募2/3 期

A comparison between ultrasound guided supraclavicular and infraclavicular approach to brachial plexus block for upper limb surgery: a randomized observer blinded study

Dr Anis Fathima1 个研究点 分布在 1 个国家目标入组 64 人开始时间: 2019年7月8日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
64
试验地点
1
主要终点
Group A- block by infraclavicular approach

研究概览

简要总结

Upperlimb surgeries canbe performed under general or regional anaesthesia. Regional anaesthesiaoffers  several advantages over general  anaesthesia such as aconscious patient , avoidance of polypharmacy and airway Intervention, betterhemodynamics, good post- operative analgesia, early resumption of activities,reduced hospital stay and improved functional outcome. Brachial plexus block atthe level of the clavicle can anaesthetize all four distal upper extremitynerve territories producing an intense blockage. Supraclavicular brachialplexus block is a popular technique for upper limb surgeries because of its quickonset and high success rate.This is because at this level, thebrachial plexus elements are tightly grouped and produces a good neurologicalblock. Corner pocket sparing and thereby a less dense ulnar blockade is aproblem in supraclavicular block.  So supraclavicular blockade requires atwo point injection.  There is a  possibility of horner’s syndrome,phrenic nerve palsy and pneumothorax which may also be considered as itsdisadvantage. The main advantage of infraclavicular block isthe fewer incidences of complications with reduced the risks of inadvertentlung/pleural puncture and avoidance of injury to the neurovascular structuresin the neck. It is an ideal site for catheter technique for continuous infusionof local anaesthetics. There is lesser incidence of ulnar nerve sparing withsingle point injection. The disadvantage is that plexus is situated deeper atthis level and the angle of approach is more acute. This makes thevisualization of the relevant anatomy and the needle tip, challenging ininexperienced hands and in obese patients. Although both supraclavicularand infraclavicular blocks can be performed for upper limb surgeries,anaesthesiologists often have an inclination to supraclavicular block overinfraclavicular block because of an ease of administration. The advent ofreal time ultrasound helps in direct visualisation of nerves and theirsurrounding anatomy. It also allows for continuous   observation of the needle tip and the spread of local anaesthetics, reducedlocal anaesthetic dose required to achieve a good block, avoidance of injury tothe nearby vascular structures making ultrasound guided brachial plexus blockhighly appealing to anaesthesiologists. The rational of this study is toevaluate the efficacy of ultrasound guided infraclavicular approach of brachialplexus block compared to ultrasound guided supraclavicular approach of brachialplexus block in upper limb surgeries.

研究设计

研究类型
Interventional
分配方式
Permuted block randomization, fixed
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Patients according to American Society of Anaesthesiologists grade 1 or
  • 2.Age between 18-60 years 3.Surgeries involving upper limb (hand and forearm) lasting more than 1 & 1/2 hours.

排除标准

  • BMI morethan 30 kg/m2
  • Pregnant women
  • Bleeding disorders, anticoagulant therapy or deranged coagulation profile
  • Pre-excisting motor or sensory deficit in the operative limb
  • Infection in the area of injection 9.Hypersensitivity to local anaesthetic agents.

结局指标

主要结局

Group A- block by infraclavicular approach

时间窗: 24 - 48 hrs

Group B- block by supraclavicular approach

时间窗: 24 - 48 hrs

To compare the onset of sensory and motor blockade of brachial plexus between

时间窗: 24 - 48 hrs

次要结局

  • 1.To compare the duration of sensory and motor block between two Groups.(2.To compare the occurrence of ulnar nerve sparing between the two groups.)

研究者

发起方
Dr Anis Fathima
申办方类型
Other [Dr Anis Fathima]

研究点 (1)

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