Differences in Ventilatory Function, Body Composition, and Cardiorrespiratory Fitness According to Training Status

Not Applicable

Recruiting

• Conditions: Body Composition; Cardiovascular Health; Ventilatory Physiology

• Registration Number: NCT06246760
• Lead Sponsor: Universidad Politecnica de Madrid

Brief Summary

The goal of this cross-over study is to evaluate the physiological response to exercise and body composition according to training status in participants with a wide spectrum of fitness states. The main questions it aims to answer are:

* Which are the physiological differences across participants with different training status?

* Which are the body composition differences across participants with different training status?

Detailed Description

To satisfy the objective of the project, participants will perform an incremental test until volitional exhaustion. During this test, respiratory gases will be measured via a gas analyser as well as the cardiac response via an electrocardiogram. The same participants will have their body composition measured by dual X-ray densitometry (DXA).

Study Timeline

• Study Start: 2000-01-01
• Study First Submitted: 2024-01-30
• Study First Submitted QC: 2024-01-30
• Study First Posted: 2024-02-07
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-03
• Last Update Posted: 2025-04-08
• Primary Completion: 2030-01-01
• Study Completion: 2030-01-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1272

Inclusion Criteria

• Be in enough physical fitness to perform the incremental test to volitional exhaustion.

Exclusion Criteria

• Present any health condition preventing to perform the incremental exercise test until volitional exhaustion.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Training status	breath-by-breath during the whole test	Oxygen uptake at ventilatory threshold 1, ventilatory threshold 2 and maximal oxygen uptake
Body composition	one determination before the test	Fat mass (kg), fat free mass (kg), fat mass percentage, fat-free mass (FFM) percentage, weight (kg), and height (m). These variables are assesed by dual-energy X-ray absorptiometry (DXA).
Bone mineral density	one determination before the test	Total, lumbar spine and femoral neck bone mineral density (g/cm\^2). These variables are assesed by dual-energy X-ray absorptiometry (DXA).

Trial Locations

Locations (1)

Faculty of physical activity and sport sciences; 🇪🇸 Madrid, Comunity of Madrid, Spain