Comparison of two drugs (dexmedetomidine and midazolam)which calm down and decreases anxiety in patients undergoing medical thoracoscopy - a randomized controlled pilot study
Phase 4
Completed
- Conditions
- Health Condition 1: J449- Chronic obstructive pulmonary disease, unspecifiedHealth Condition 2: null- Patients would be suffering from lung disease and planned for thoracoscopy
- Registration Number
- CTRI/2018/06/014377
- Lead Sponsor
- All India Institute of Medical Sciences AIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
weight between 30 and 80 kg
ASA- I-III patients undergoing medical thoracoscopy under conscious sedation
Informed written consent
Exclusion Criteria
a)Intubated patients
b)patients with a known allergy or intolerance to midazolam, fentanyl and dexmedetomidine
c)pregnant or nursing women
d)patients with a mental disorder preventing appropriate judgment concerning study participation
e)hypersensitivity or allergy to the study drugs
f)uncontrolled hypertension (uncontrolled blood pressure >140/90 mmHg)
g)major abnormalities of liver function, ischemic heart disease and severe respiratory disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effects of dexmedetomidine and midazolam in conscious sedation for patients undergoing medical thoracoscopy on pulmonologist and patient satisfaction.Timepoint: Pulmonologist satisfaction at the end of procedure and patient satisfaction at 2 hours after the procedure will be evaluated.
- Secondary Outcome Measures
Name Time Method To compare the effects of dexmedetomidine and midazolam in conscious sedation for patients undergoing medical thoracoscopy on hemodynamic variables.Timepoint: during the procedure