Sickle Cell Children's Exercise Study Determining the Effects of a Targeted Exercise Training Program on Neuromuscular Performance, Locomotor Efficiency, and Exercise Tolerance in Children With Sickle Cell Disease.
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 20
- 试验地点
- 4
- 主要终点
- knee extension strength
研究概览
简要总结
The Sickle Cell Children's Exercise Study (SuCCESs) will explore the feasibility and effects of a moderate intensity strengthening, balance, speed, and agility intervention program in children with sickle cell disease.
详细描述
Participants will perform the baseline assessment and after six weeks of performing the SuCCESs program the participants will perform a post-intervention assessment. Participants will be asked to attend a total of six physical therapy in-person sessions (1x/week) at the University of Maryland Department of Physical Therapy and Rehabilitation Science and to perform 12 home program sessions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
盲法说明
One physical therapist will perform the pre- and post-test assessment measures and another pediatric physical therapist will perform the intervention sessions.
入排标准
- 年龄范围
- 6 Years 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children 6-17 years of age diagnosed with sickle cell disease
排除标准
- •Diagnosis of neurological disorder, not related to sickle cell disease
- •Lower extremity injury such as a fracture with a cast
研究组 & 干预措施
Physical Therapy Exercise
There will be no control group and only one intervention delivered
干预措施: SuCCESs (Behavioral)
结局指标
主要结局
knee extension strength
时间窗: week 1 and week 7
dynamometry to measure knee extension strength
Rate of Muscle Activation
时间窗: week 1 and week 7
Electromyography used to measure rate of muscle activation
exercise tolerance
时间窗: week 1 and week 7
6-Minute Walk Test used to measure exercise tolerance
locomotor efficiency
时间窗: week 1 and week 7
oxygen uptake used to measure locomotor efficiency
number of sessions attended
时间窗: throughout the entire study week 1, weeks 2-6, six weeks of intervention, and week 7
attendance
次要结局
未报告次要终点
研究者
victoria marchese
professor, Chair
University of Maryland, Baltimore