Repetitive Transcranial Magnetic Stimulation and Postoperative Neurocognitive Recovery
- Conditions
- Older PatientsCognitive ImpairmentRepetitive Transcranial Magnetic StimulationDelayed Neurocognitive RecoveryPostoperative Neurocognitive Disorder
- Registration Number
- NCT06482749
- Lead Sponsor
- Peking University First Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- All
- Target Recruitment
- 568
Inclusion Criteria:<br><br> 1. Aged =65 years;<br><br> 2. Patients with preoperative mild to moderate cognitive impairment, defined as<br> 9<Montreal Cognitive Assessment (MoCA)<26;<br><br> 3. Scheduled for elective non-cardiac surgery under general anesthesia, with an<br> expected surgical duration of >2 hours;<br><br> 4. Expected to stay in hospital of at least 5 days after surgery.<br><br>Exclusion Criteria:<br><br> 1. Left-handed;<br><br> 2. Primary school education level or below;<br><br> 3. Comorbid diseases including mental illness, intellectual disability, auditory and<br> visual dysfunction, language impairment, severe neurological disorders, or other<br> diseases that impede the completion of evaluation;<br><br> 4. Neurosurgery;<br><br> 5. Presence of contraindications to rTMS treatment, including epilepsy, pregnant or<br> lactating women, or with a metal or electric implanted device (e.g., deep brain<br> stimulator, ventriculoperitoneal shunt, aneurysm clip, pacemaker, cochlear implant,<br> or surgical staples on the scalp);<br><br> 6. Other situations that are deemed unsuitable for inclusion in the study.
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of delayed neurocognitive recovery
- Secondary Outcome Measures
Name Time Method Incidence of delirium;Incidence of neurocognitive disorder at 30 days after surgery;Incidence of neurocognitive disorder at 180 days after surgery