Effect of Repetitive Transcranial Magnetic Stimulation in Patients with Generalized Anxiety Disorder: An open-label pilot study
- Conditions
- Generalized Anxiety Disorder patientsGeneralized Anxiety DisorderGADTMSrTMSTranscranial magnetic stimulation
- Registration Number
- TCTR20210507006
- Lead Sponsor
- Siriraj Research Fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 20
1. Patient with Generalized Anxiety Disorder according to DSM-5 who is interviewed by psychiatrists or psychiatric residents and confirmed by M.I.N.I.
2. Hamilton anxiety rating scale (HAM-A) at least 18
3. Montgomery and Asberg Depression Rating Scale (MADRS) < 20
4. Stable dose of medication treating GAD except for benzodiazepine drugs as needed
1. Contraindication for rTMS which are history of seizure, using implant pacemaker, using cochlear implant, using metallic implant, using ocular implant and having aneurysmal clip or stent
2. Psychosis within 1 months before participating in research
3. High risk for suicide within 1 months before participating in research
4. Unstable medical condition such as heart failure, coronary heart disease, ischemic or hemorrhagic stroke, or bone fracture
5.Alcohol use disorder/sedative use disorder with
acutely abstinent within 1 week before participating in research
6. Cannot use Thai language
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response rate (Anxiety) at 30 sessions after rTMS or 6 weeks Reduction of Hamilton Anxiety Rating Scale (HAM-A) at least 50%
- Secondary Outcome Measures
Name Time Method