Effects of Non-invasive Brain Stimulation combined with Action Observation Exectuion on Stroke Motor Functio
- Conditions
- Weakness in the upper extremity in patients with strokeStrokeMotor function
- Registration Number
- TCTR20240416009
- Lead Sponsor
- Mahidol University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 22
1. First subcortical stroke within 1-3 months as reported by the CT/ MRI
2. Age between 40-80 years
3. Right-handed based on the Edinburgh Handedness Inventory
4. Being able to understand and follow simple commands based on performance on the mini-mental state examination(MMSE) (cutoff>23)
5. Fugl-Meyer Assessment (FMA) upper extremity level at moderate (29-42 scores)
6. Normal visual field and hearing
7. Independent sitting for at least 1 hour
1. No contraindications of using rTMS (seizure, an intracranial metallic implant, MRI-incompatible pacemakers) 2. Other neurological problems (Parkinson's disease) 3. Severe sensory impairment (score = 0 by the FMA-UE of sensation and proprioception) 4. Severe joint pain on at least 3 of 5 UE joints (FMA-UE pain score=0) 5. Severe limited joint movement (FMA-UE passive joint motion of shoulder and elbow score=0) 6. Aphasia 7. Visual neglect ( screening by NIHSS-neglect score more than 1) 8. Ideomotor apraxia ( imitation meaningless of gesture; error score > 3)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hand function at 1 week after end of the intervention Wolf Motor Function Test,corticospinal excitability at 1 week after end of the intervention transcranial magnetic stimulation
- Secondary Outcome Measures
Name Time Method Self-reported impact on quality of life at 1 week after end of the intervention Stroke Impact Scale