Effects of Repetitive Transcranial Magnetic Stimulation on Mild Depressive Symptoms
- Conditions
- Not Applicable
- Registration Number
- KCT0003238
- Lead Sponsor
- Ewha Womans University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 80
Healthy volunteers between the ages of 19 and 65
- Reported current stress and tension symptoms during psychiatric interview or on self-report questionnaire (scoring more than 50% on the Visual Analog Scale, VAS)
- Reported mild depressive symptoms during psychiatric interview or on self-report questionnaire (scoring between 8~16 on Hamilton Rating Scale for Depression, HAM-D)
- Diagnosed with any major medical or neurological disorders assessed during medical history taking, physical examination or experimental tests
- Diagnosed with any axis 1 psychiatric disorders including major depressive disorder (bipolar disorder, alcohol dependence, schizophrenia, etc.) evaluated with a structured clinical interview
- History of traumatic brain injury with loss of consciousness or convulsions
- Planning for pregnancy during the period of study participation, currently pregnant or breastfeeding
- Had taken psychotropic drugs within the past 2 months before study participation
- Any contraindications to MRI (i.e., claustrophobia, metallic foreign devices in the body)
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in the depressive symptom levels assessed by the Hamilton Rating Scale for Depression;Change in the depressive symptom levels assessed by the Beck Depression Inventory
- Secondary Outcome Measures
Name Time Method Change in brain structure assessed by magnetic resonance imaging data;Change in brain function assessed by magnetic resonance imaging data;Change in brain metabolism assessed by magnetic resonance imaging data