To find out the effect of Repetitive Transcranial Magnetic Stimulation and Task-specific Trunk Control training in person having Parkinsons Disease

Not yet recruiting

Brief Summary: This study was a Randomized Controlled Trial (RCT) investigating the combined effect of Repetitive Transcranial Magnetic Stimulation (rTMS) and Task-specific Trunk Control Training on postural stability in individuals with Parkinson’s Disease (PD). A total of 16 participants met the inclusion criteria and completed the study.

The study was conducted at multiple physiotherapy and neurorehabilitation centers in Patiala, India. Ethical approval was obtained, and informed consent was secured from all participants.

Participants were randomly divided into two groups:

Group A: Received rTMS, Task-specific Trunk Control Training, and Conventional Physiotherapy.

Group B: Received Sham rTMS, Task-specific Trunk Control Training, and Conventional Physiotherapy.

Assessments were conducted at baseline, Day 7, and Day 15 using:

MDS-UPDRS-III (Movement Disorder Society-Unified Parkinson’s Disease Rating Scale - motor part

m-CTSIB (Modified Clinical Test of Sensory Interaction in Balance)

PDQL (Parkinson’s Disease Quality of Life Scale)

The intervention lasted 3 weeks (5 days per week), with progressive exercises focusing on balance, trunk control, and functional mobility. Post-intervention data were analyzed to evaluate improvements in motor function, balance, and quality of life.

Recruitment & Eligibility

Inclusion Criteria

Individuals who will be willing to participate and able to give informed consent.
Individuals diagnosed with Parkinson’s disease according to ICF domains.
Individuals with Hoehn & Yahr stage between 2 and 4.
Individuals with a MMSE score more than 24.
Individuals with balance deficits (mPOMA score less than 23).

Exclusion Criteria

Individuals with any pre-existing neurological disease other than PD.
Individuals with any magnetic-sensitive metallic implants close to the stimulation site.
Any systematic illness.
Presence of any orthopedic disease, visual problems, or vestibular disorders that could affect balance.
Surgery in lower limb and spine.
Non-cooperative individuals.

Primary Outcome Measures

Name	Time	Method
Movement Disorder Society-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS)- Motor Part -III	At baseline, day 7, day 15

Secondary Outcome Measures

Name	Time	Method
Quality of life-PDQL (Parkinson’s disease quality of life)	At Baseline, day 7, day 15
Modified Clinical Test of Sensory Interaction in Balance (m-CTSIB)	At baseline, Day 7, Day 15

Locations (1): Punjabi University
🇮🇳
Patiala, PUNJAB, India
Punjabi University
🇮🇳Patiala, PUNJAB, India
Dr Narkeesh Arumugan
Principal investigator
9417802662
narkeesh@gmail.com