Postural responses to balance perturbations in individuals with Supratentorial Stroke and Idiopathic Parkinson's Disease

Recruiting

• Conditions: Parkinson's Disease; Stroke; 10029305

• Registration Number: NL-OMON36220
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

All participants:
- Functional Ambulation Categories 3-5
- Age 18 years and older
- Ability to stand independently (on bare feet) for at least 30 minutes
Stroke patients:
- Unilateral Supratentorial Stroke longer than 6 months ago
Parkinson patients:
- Idiopathic Parkinson's Disease
- Hoehn & Yahr Stages 1-3

Exclusion Criteria

- Any other neurological or musculoskeletal disorder affecting balance
- Any inability to cooperate with the assessments and to give written informed consent
- Medication negatively affecting balance (e.g. neuroleptics, antidepressants, anticonvulsants, sedatives).

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The stepping threshold, defined as the highest perturbation intensity (in m/s2)<br /><br>at which balance is maintained with a feet in place response.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Kinematic variables such as joint angles and Centre of Mass (CoM)<br /><br>- Margin of Stability defined as the minimum distance between the vertical<br /><br>projection of the CoM and the border of the Base of Support (BoS) during<br /><br>perturbations at the stepping threshold.<br /><br>- EMG (electromyographic) variables such as onset latency and amplitude. </p><br>