跳至主要内容
临床试验/CTRI/2025/07/091329
CTRI/2025/07/091329尚未招募1/2 期

Single arm clinical study to assess the efficacy of Japakusum lepa in Indralupta with special refernce to Alopecia Areata

LRP Ayurvedic Medical College and Research Centre1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年8月5日最近更新:

试验速览

阶段
1/2 期
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
Evaluation the efficacy of japakusum lepa in Indralupta

研究概览

简要总结

Ayurveda stands as the oldest surviving medical system globally with long record of clinical experience. The central objective of ayurveda is to promote individual well being by employing both preventive and curative method. Our Acharya divided ayurveda into 8 branches which deals with different parts of body. Among the astanga, urdhavaka chikitsa or shalakya chikitsa is described urdhvanga chikitsa is also known as urdhava jatrugata chikitsa .

In todays world of advanced science many people still turn to Ayurveda for treating chronic disorders  for beauty treatments, primarily due to the minimal adverse effects associated with Ayurvedic medicines. Hair plays a significant role in personality, beauty, and confidence. For centuries, people have used various herbal packs, washes, and hairstyles to enhance their appearance. Common hair issues that affect an individuals beauty include graying, hair loss, roughness, brittle hair, split ends, and dandruff.

Indralupta described kapalgatroga by AcharyaVaghbhatta and in kshudraroga by Acharya Sushrut. Alopecia areata is an autoimmune disease characterized by patchy hair loss commonly on scalp and facial region can be correlated with Indralupta. Alopecia areata has become a significant health concern in the 21st century, largely due to changes in lifestyle, the widespread adaptation of western culture, unhealthy dietary habits and race for cosmetics.

Even though medical science has advanced to a great extent in the field of cosmetology and trichology, but still there is no definite cure for present condition. Treatment option include topical and systemic steroids. Topical irritants and immunotherapy which create an allergic reaction with the production of T-suppressor cells which inhibit an auto immune reaction.

Minoxidil  is an anti-hypertensive vasodilator primarily treating for hair loss common side effect includes eye irritation, itching redness and irritation at application site along with unwanted hair growth in other areas. Due to side effect and limitation of contemporary science, effective and harmless treatment procedure is expected from alternative medical science.

Ayurveda has great potential to treat such autoimmune disease. A study is being planned to develop an efficient remedy that could greatly beneficial for the patient who is suffering from Indralupta.

Acharya Sushruta has preferred upkrama like application of lepa etc in some cases. Indralupta is one such disorder where lepa has been advocated. lepa refer to application of medicated paste or packs on the affected area. The goal of lepa treatment in Indralupta is to stimulate growth and balance the doshas.

研究设计

研究类型
Interventional
分配方式
Other

入排标准

年龄范围
18.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • 1 Patients having signs and symptoms of Indralupta 2 Patient of Indralupta from any community irrespective of their religion socioeconomic status hygiene condition 3 Patient willing to give consent for clinical trial.

排除标准

  • Patients below 18yrs and above 50 years of age group 2) Patients having systemic disease with complications which can lead to interference with the study 3) Unstable patients 4) Any other local treatment for Indralupta 5) Pregnant women 6) Patient on chemotherapy.

结局指标

主要结局

Evaluation the efficacy of japakusum lepa in Indralupta

时间窗: 21 days

次要结局

  • To reduce the indralupta in 21 days To study the literature related to concept of indralupta To study the concept of japakusum lepa in indralupta(21 days)

研究者

发起方
LRP Ayurvedic Medical College and Research Centre
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Nikita Arjun Thorat

LRP Ayurvedic Medical College And Research Centre

研究点 (1)

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