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临床试验/NCT03543280
NCT03543280Unknown不适用

Evaluation of the Value of Cerebral Perfusion Scintigraphy in the Study of Post-stroke Fatigability

University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家目标入组 32 人开始时间: 2018年2月23日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
32
试验地点
1
主要终点
Evaluate fatigue symptoms in stroke patients

研究概览

简要总结

At present there is no consensus for post-stroke imaging except for the realization of early cerebral CT at 24 hours post-thrombolysis. The use of cerebral perfusion scintigraphy would predict the course of a stroke. Indeed, it has been shown that a good perfusion is linked to a good evolution of the neurological deficit. This test is used routinely to evaluate cerebral perfusion in patients with stroke. This technique was also used to study the mechanisms of post-stroke aphasia and to highlight neuronal disconnections after stroke, a reflection of the functioning of neural networks.

Neuropsychological tests are almost always done at 3 months. Fatigue is studied: PSF scale at 3 months, 6 months and 2 years. Research needs to be continued in this area because the pathophysiology remains unknown and the symptoms are disabling for patients. Using cerebral perfusion imaging would bring elements of understanding of this mechanism and ultimately improve the management of patients.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Patients: 18 to 60 years old at the initial diagnosis
  • Admission for transient ischemic attack, stroke, dissection, TVC
  • RANKIN less than or equal to 2
  • Neuropsychological tests at +3 months: MoCA> 26 (to eliminate cognitive deteriorations too important for the good realization of the battery)
  • Absence of psychiatric history
  • Absence of psychotropic medication
  • No history of stroke
  • No complaint of pre-stroke fatigue
  • Having signed the consent form

排除标准

  • Impossibility of giving the subject or his family enlightened information (subject in emergency situation, difficulties in understanding the subject, etc.)
  • Subject under the protection of justice
  • Subject under guardianship or curatorship
  • Refusal of the patient to participate in the study

结局指标

主要结局

Evaluate fatigue symptoms in stroke patients

时间窗: After the period following a stroke: 1 month

次要结局

未报告次要终点

研究者

发起方
University Hospital, Strasbourg, France
申办方类型
Other
责任方
Sponsor

研究点 (1)

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