Effect of Smoking Cessation on Non-surgical Periodontal Therapy

Not Applicable

Completed

• Conditions: Periodontitis
• Interventions: Behavioral: Smoking cessation therapy; Procedure: Non-surgical periodontal therapy

• Registration Number: NCT02493270
• Lead Sponsor: University of Sao Paulo

Brief Summary

The aim of this prospective study is to verify the efficacy of smoking cessation on non-surgical periodontal therapy in adult subjects with chronic periodontitis.

Smokers that were willing to quit received periodontal treatment and concurrent smoking cessation therapy. Periodontal maintenance was performed every 3 months. A calibrated examiner, blinded to smoking status, assessed periodontal status, gathered demographic and behavioural information with a structured questionnaire and measured air carbon monoxide concentration measurements.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-05
• Primary Completion: 2014-05
• Study Completion: 2014-06
• Study First Submitted: 2015-07-02
• Study First Submitted QC: 2015-07-06
• Study First Posted: 2015-07-09
• Status Verified: 2016-04
• Last Update Submitted: 2016-04-13
• Last Update Posted: 2016-04-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 177

Inclusion Criteria

• subjects were willing to stop smoking
• >10 teeth
• periodontitis (30% or more of their teeth with proximal CAL ≥ 5 mm

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Exclusion Criteria

• systemic conditions considered as risk factors for periodontal disease,
• periodontal therapy in the last 6 months
• continuous systemic use of anti-inflammatory or steroidal drugs

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Adjunctive smoking cessation	Non-surgical periodontal therapy	non-surgical periodontal therapy and concurrent smoking cessation therapy
Adjunctive smoking cessation	Smoking cessation therapy	non-surgical periodontal therapy and concurrent smoking cessation therapy

Primary Outcome Measures

Name	Time	Method
Change in Clinical Attachment Level (millimeters) after 24 months	baseline and 24 months

Secondary Outcome Measures

Name	Time	Method
Change in Gingival recession (millimeters) after 24 months	baseline and 24 months
Change in Pocket depth (millimeters) after 24 months	baseline and 24 months
Change in bleeding on probing (percentage of sites with bleeding) after 24 months	baseline and 24 months
Change in visible plaque (percentage of sites with visible plaque) after 24 months	baseline and 24 months