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Clinical Trials/IRCT20200117046160N2
IRCT20200117046160N2
Completed
N/A

Evaluation effects of multimodal rehabilitation on recovery of ICU Acquired weakness following coronavirus infection(COVID-19)

Mazandaran University of Medical Sciences0 sites27 target enrollmentTBD

Overview

Phase
N/A
Intervention
Not specified
Conditions
Not specified
Sponsor
Mazandaran University of Medical Sciences
Enrollment
27
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Definitive diagnosis of Coronavirus based on Polymerase Chain Reaction (PCR) or lung CT Scan and expert opinion
  • Intensive Care Unit Acquired Weakness (ICUAW) diagnosis based on the following criteria: \- Total muscle strength points of 6 muscle groups bilaterally (Forearm flexion, wrist extension, Hip flexion, knee extension, Ankle dorsiflexion, Arm abduction) in manual examination according to Medical Research Council(MRC) criteria is less than 48 (out of 60 total points) \- Normal consciousness based on Glasgow Coma Scale(GCS) (score 15 out of 15\) \- Opinion of an Anesthesiologist or Intensive Care Fellowship \- History of hospitalization in ICU for more than 48 hours (with and without the need for Mechanical ventilation)

Exclusion Criteria

  • Loss of consciousness
  • Uncontrolled hypertension means: resting systolic blood pressure\> 180 mmHg and / or resting diastolic blood pressure\> 110 mmHg
  • Uncontrolled sinus tachycardia (\> 120 beats / min) or Sinus bradycardia (HR \<60\)
  • Concurrent heart disease such as: Decompensated heart failure and evidence of Ischemic heart disease, Symptomatic arrhythmia
  • Hypoxia at rest (Oxygen saturation (SPO2\)\< 88%)
  • Pulmonary artery hypertension (Pulmonary Artery Pressure(PAP) \> 30mmHg)
  • Fever or Acute systemic disease
  • Uncontrolled Diabetes Mellitus( DM)
  • Severe Orthopedic or Neurological problems that prevent exercise
  • Other metabolic conditions such as: Acute thyroiditis, Hyperkalemia, Hypokalemia and Hypovolemia (Until adequate treatment)

Outcomes

Primary Outcomes

Not specified

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