Assessment of Dried Blood Spot Thyroglobulin in Pregnant Women to Redefine the Range of Median Urinary Iodine Concentration That Indicates Adequate Iodine Intake
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,900
- 试验地点
- 1
- 主要终点
- Urinary iodine concentration and Thyroglobulin concentration in pregnant women.
研究概览
简要总结
To avoid iodine deficiency and its consequences in pregnant women and their offspring, women should reach a sufficient iodine intake long before conception. To monitor iodine status, median urinary iodine concentration (UIC) is widely used in pregnant women (PW). Thyroglobulin (Tg) us another marker used to assess iodine status . In this study, urine samples as well as dried blood spots will be collected to measure UIC and Tg (as well as other hormones to define thyroid function) in PW. The results shall be used to reassess the threshold which defines iodine status in PW according to UIC.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 44 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Generally healthy
- •No major medical illness, no thyroid disease, and taking no chronic medication
- •No use of iodine containing dietary supplements
- •No use of iodine-containing X-ray /CT contrast agent or iodine containing medication within the last year
- •Aged between 18 and 44 at enrollment
- •Singleton pregnancy
- •Non-smoking
- •Residence at study site since 12 months or longer
排除标准
- 未提供
结局指标
主要结局
Urinary iodine concentration and Thyroglobulin concentration in pregnant women.
时间窗: June 2018
Analysis of urine and blood samples to find urinary iodine concentration and Thyroglobulin concentration of each participant.
次要结局
未报告次要终点
研究者
Prof. Michael B. Zimmermann
Prof. Dr.
Swiss Federal Institute of Technology