Evaluating the Endometrial Receptivity of FET Patient by Ultrasounicelastography

Not Applicable

Completed

• Conditions: Assisted Reproductive Technology; Ultrasonography
• Interventions: Other: Ultrasounicelastography

• Registration Number: NCT03881072
• Lead Sponsor: Jinling Hospital, China

Brief Summary

Prospective clinical study ：observing the correlation between endometrial elasticity score, endometrial blood flow index (PI, RI, S/D, endometrial thickness, morphology) and clinical pregnancy rate. In order to find a non-invasive, convenient and comprehensive evaluation method of evaluating the endometrial receptivity, and to provide effective means for the frozen embryo transplantation patients to improving pregnancy outcome.

Detailed Description

Randomly selecting 20-40 years patients were prepared to accept frozen embryo transplant ; HRT cycle preparation of endometrium；choosing HRT plan to prepare the transplantation endometrium.Establishing a strict standard of exclusion and exclude standard to exclude endometrial lesions and underlying disease.The patients were given elastography for 5-7 days afterEndometrium transformation.Observing the correlation between endometrial elasticity score, endometrial blood flow index (PI, RI, S/D, endometrial thickness, morphology) and clinical pregnancy rate. In order to find a non-invasive, convenient and comprehensive evaluation method of evaluating the endometrial receptivity, and to provide effective means for the frozen embryo transplantation patients to improving pregnancy outcome.

Study Timeline

• Study Start: 2017-10-01
• Primary Completion: 2018-01-10
• Study First Submitted: 2018-09-12
• Study Completion: 2018-12-10
• Status Verified: 2019-03
• Study First Submitted QC: 2019-03-18
• Last Update Submitted: 2019-03-18
• Study First Posted: 2019-03-19
• Last Update Posted: 2019-03-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

1. the volunteers voluntarily signed the informed consent.
2. female patients between 20-40 years old.
3. HRT cycle.
4. no uterine cavity operation was performed within 3 months.

Exclusion Criteria

1. endometrial polyps, abnormal uterine cavity, intrauterine adhesions and dysplasia of uterus.
2. hydrosalpinx was not ligated.
3. patients with uterine myoma and uterine fibroids;

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Ultrasounicelastography	Ultrasounicelastography	Ultrasounicelastography:non-invasive, convenient and comprehensive evaluation method.

Primary Outcome Measures

Name	Time	Method
endometrial receptivity	Month 12	Observing the correlation between elasticity score, endometrial blood flow index (PI, RI, S/D, endometrial thickness, morphology) and clinical pregnancy rate.

Trial Locations

Locations (1)

Yao Bing; 🇨🇳 Nanjing, Jiang Su, China