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Clinical Trials/NCT05561881
NCT05561881
Completed
Not Applicable

Comparison of Efficacy Between Ultra-sound Genicular Nerve Block Versus the Popliteal Artery and the Capsule of the Posterior Knee(IPACK) Block for Knee Arthroscopic Surgery

Assiut University1 site in 1 country50 target enrollmentDecember 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Genicular Nerve Block
Sponsor
Assiut University
Enrollment
50
Locations
1
Primary Endpoint
Pain Visual Analogue Scale (VAS)
Status
Completed
Last Updated
7 months ago

Overview

Brief Summary

Postoperative pain management after knee arthroscopic surgery continues to evolve with better treatment strategies being formulated to improve patient satisfaction, and clinical outcomes and reduce opioid use in the immediate postoperative period. appropriate perioperative pain management has been shown to result in faster recovery and rehabilitation leading to better functional outcomes in patients undergoing knee arthroscopic surgery. this has necessitated the development of multimodal analgesics. peripheral nerve blockade has been reported to deliver optimal postoperative pain relief and is increasingly preferred in patients undergoing arthroscopic procedures and various different techniques such as sciatic nerve block, femoral nerve block, and genicular block have been described.

Detailed Description

The genicular nerves include branches from the femoral, common peroneal, saphenous, tibial, and obturator nerves which innervate the knee capsule. the superolateral, superomedial, and inferomedial branches of the genicular nerve were reported to be in proximity to the periosteum of the tibia and femur, and the superolateral, inferolateral, superomedial, and inferomedial quadrant of the anterior knee joint were shown to be innervated by superior lateral, inferior lateral, superior medial and inferior medial branches of the genicular nerve, respectively alongside the branches of peroneal and femoral nerves Thus, a genicular nerve block specifically Targets these branches which innervate the knee joint for the management of postoperative pain in arthroscopic surgery. On the other hand, the interspace between the popliteal artery and capsule of the knee(IPACK) block provides analgesia on the posterior knee joint, and the application of a genicular or IPACK block has been proven to be associated with promising outcomes following arthroscopic surgery

Registry
clinicaltrials.gov
Start Date
December 1, 2022
End Date
March 1, 2025
Last Updated
7 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Amani Hassan Abdel-Wahab

assistant professor

Assiut University

Eligibility Criteria

Inclusion Criteria

  • age 20\_60 years
  • American Society of anthologist class I-III
  • BMI18\_35 kg/m2
  • scheduled for primary unilateral knee arthroscopic surgery

Exclusion Criteria

  • known allergy to local anesthesia
  • contraindication to local anesthesia injection (e.g., infection at the site of injection
  • contraindication to spinal anesthesia (e.g., coagulopathy)
  • patients with preexisting motor or sensory deficit in lower extremities
  • insulin or non-insulin-dependent diabetes mellitus
  • systemic corticosteroids use within 30 days
  • history of arrhythmia or seizures
  • severe renal insufficiency
  • patient refusal

Outcomes

Primary Outcomes

Pain Visual Analogue Scale (VAS)

Time Frame: first postoperative 24 hours

VAS in the first postoperative 24 hours

Study Sites (1)

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