Comparison of the Effectiveness of Ultrasound-Guided Perimeniscal Steroid and Dextrose Injections in Knee Osteoarthritis
Overview
- Phase
- Phase 4
- Intervention
- Dextrose 5% in water
- Conditions
- Gonarthrosis
- Sponsor
- Kastamonu University
- Enrollment
- 31
- Locations
- 1
- Primary Endpoint
- Visual Analogue Scale
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Introduction: The primary goal of treating knee osteoarthritis is to reduce pain and improve the patient's quality of life. Medial meniscal extrusion is a condition that is linked to pain and disability in knee osteoarthritis and can be identified through ultrasound. For patients with medial meniscal extrusion, perimeniscal corticosteroid injection has been shown to be a helpful addition to primary treatment for moderate to severe pain relief. Dextrose prolotherapy has also been found to provide periarticular benefits for knee osteoarthritis. This study aims to compare the effectiveness of ultrasound-guided perimeniscal corticosteroid and perimeniscal dextrose injections in patients with osteoarthritis, medial knee pain, and medial meniscal extrusion.
Method: Patients with medial knee pain and meniscal extrusion were randomly divided into two groups using the double-block randomization method. Group 1 included 15 patients who were administered an ultrasound-guided perimeniscal steroid injection, while Group 2 included 16 patients who were administered an ultrasound-guided perimeniscal dextrose injection. The patients' pain levels were evaluated using the Visual Analog Pain Scale (VAS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) before and one week, one month, and three months after the injection.
Investigators
Gamze Gul Gulec
Doctor
Kastamonu University
Eligibility Criteria
Inclusion Criteria
- •Grade 2-4 knee osteoarthritis,
- •Aged 40 to 79
- •Chronic medial knee pain persisting for more than 3 months.
- •Ultrasound screening found medial meniscal extrusion of more than 3 mm
- •A Visual Analog Scale (VAS) score of at least 4.
Exclusion Criteria
- •a skin infection at the injection site, a prior history of inflammatory arthropathy, a prior history of knee injection within the last 3 months, knee synovitis pes anserine bursitis scheduled for surgery
Arms & Interventions
Group 1
patients who had perimeniscal 5 % dextrose injection
Intervention: Dextrose 5% in water
Group 2
patients who had perimeniscal triamcinolone injection
Intervention: Triamcinolone Hexacetonide
Outcomes
Primary Outcomes
Visual Analogue Scale
Time Frame: At the beginning, 1.,4., 12. week
The pain VAS is a unidimensional measure of pain intensity, used to record patients' pain progression or compare pain severity between patients with similar conditions.VAS is comprised of a horizontal line of 10 cm in length. A measurement of 0 cm indicates the absence of pain, whereas a measurement of 10 cm signifies the most severe pain that one can conceive. Patients are instructed to assess the intensity of discomfort by indicating a point on this line.
Secondary Outcomes
- Western Ontario and McMaster University Osteoarthritis Index(At the beginning, 1.,4., 12. week)