Evaluation of Radiofrequency Neurolysis and Chemical Neurolysis of the Genicular Nerves

Not Applicable

Completed

• Conditions: Knee Osteoarthritis
• Interventions: Procedure: Genicular nerve chemical neurolysis; Procedure: Genicular nerve radiofrequency neurolysis

• Registration Number: NCT05340166
• Lead Sponsor: Diskapi Teaching and Research Hospital

Brief Summary

Knee osteoarthritis is one of the most common causes of pain and loss of function in the elderly population and is a source of socioeconomic costs. Selective denervation of the superior medial, superior lateral and inferior medial genicular nerves, which provide the sensory innervation of the knee joint, is an effective treatment method used to relieve pain and improve functional capacity. Radiofrequency neurolysis of genicular nerves (RFN) is accepted as an effective technique for the treatment of knee pain. However, due to higher equipment costs, longer procedure times, and procedure-related pain, alternative treatments are needed.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-04-14
• Study First Submitted QC: 2022-04-15
• Study First Posted: 2022-04-22
• Study Start: 2022-04-24
• Primary Completion: 2023-06-20
• Status Verified: 2023-07
• Study Completion: 2023-07-05
• Last Update Submitted: 2023-07-06
• Last Update Posted: 2023-07-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Exclusion Criteria

• Coagulation disorders
• Rheumatoid disorders
• Infections

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Chemical Neurolysis	Genicular nerve chemical neurolysis	Chemical Neurolysis of genicular nerves
Radiofrequency Neurolysis	Genicular nerve radiofrequency neurolysis	Radiofrequency Neurolysis of genicular nerves

Primary Outcome Measures

Name	Time	Method
Numerical Rating Scale (NRS)	Change from baseline to 6 months after procedure	Pain Score Change The 11-point NRS consists of numbers between 0 and 10 where 0 indicates "no pain" and 10 indicates "maximum pain." The patient is instructed to identify one number between 0 and 10, which is best representative of their pain intensity.

Trial Locations

Locations (1)

Diskapi Yildirim Beyazit Training and Research Hospital; 🇹🇷 Ankara, Turkey