ISRCTN10994757已完成未知
A multi-centre, double-blind, randomised, controlled clinical trial of rifaximin to reduce infection in patients admitted to hospital with decompensated cirrhosis
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 78
研究概览
简要总结
2021 Thesis results in https://doi.org/10.25560/97104 (added 30/08/2023)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Clinical/biochemical/radiological +/- histological diagnosis of cirrhosis
- •2. Hospital admission with complication of cirrhosis (e.g. alcoholic hepatitis, sepsis, variceal bleeding)
- •3. Commencement on antimicrobial therapy
- •4. Aged 18 - 80 years
排除标准
- •1. C.difficile infection
- •2. HIV antibody positive
- •3. Immunosuppression (excluding low dose steroids/steroid sparing agents for AIH <20 mg or equivalent of prednisolone)
- •4. Advanced disseminated Hepatocellular Carcinoma or invasive carcinoma
- •5. eGFR < 30 on screening/randomisation
- •6. End-stage/severe cardiac, pulmonary or kidney disease
- •8. Colitis or coeliac disease
- •9. Pregnancy
- •10. Already receiving rifamixin
研究者
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