Efficacy of Triphaladi taila in the management of Hypothyroidism- An open labeled randomized control clinical trial
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Management of Hypothyroidism.
研究概览
简要总结
Hypothyroidism is one of the most common and challenging disease in today’s era. Hypothyroidism is a condition in which the thyroid gland does not produce enough Thyroxine(T4) and Triiodothyronine (T3).
Thyroid hormone act as catalyst for metabolism in whole body. In Hypothyroidism, there is Agnimandya and Meda Kapha vrudhdhi. Additionally there is condition of Avrutta vata due to excessive Kapha and Meda leading to Vatavaigunya and features of Vatavruddhi like dryness, menorrhagia. So the drugs which have Ushna,Kapha medahara, Vatanulomana, Ampachna, Srotoshodhana are useful in the management of Hypothyroidism.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient who is already taking levothyroxine medicine but having high S.TSH level ,S.TSH greater than 5.5 mIU per L.
- •Newly diagnosed patients of Hypothyroidism with S.TSH greater than 5.5 mIU per L (Sandwich chemi luminescent immuno assay method) (uncontrolled Hypothyroidism) S.Total T3 less than 80 ng per dL S.Total T4 less than 5.0 µg per dL.
排除标准
- •Patients having any other major systemic diseases like Cancer, Tuberculosis, SLE, etc.
- •Pregnant women or Lactating mothers.
- •Any other debilitating disease which may lead to fatal condition for the patient at any time.
- •Patient having history of peptic ulcers, bleeding ulcers, bleeding piles etc.
- •Patients having any drug abuse.
- •Patients with psychiatric illness Patients taking other medicines for any other acute disease.
- •If S.TSH level is more than 100mIU/L .
结局指标
主要结局
Management of Hypothyroidism.
时间窗: 40 days
Role of tailapan in management of Hypothyroidism.Serum total tsh will be assessed before and after trial.
时间窗: 40 days
次要结局
- To improve quality of life(7 days after completion of clinical trial)
研究者
Dr Purnima Jadav
Government Akhandanand ayurveda college