MRI-guided identification of response to (chemo)radiotherapy in patients with head and neck cancer
Recruiting
- Conditions
- Head and Neck Squamous Cell Carcinoma (HNSCC)Oropharyngeal cancerCancer of the oral cavityHypopharyngeal cancerLaryngeal cancerHoofd-hals kanker
- Registration Number
- NL-OMON24896
- Lead Sponsor
- niversity Medical Center Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Squamous cell carcinoma
-T2, T3 or T4 Oral cavity or pharynx
Exclusion Criteria
-Age < 18 years
-Pregnancy
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint is the predictive value of DW-MRI after the start of radiotherapy based on a single scan during treatment.
- Secondary Outcome Measures
Name Time Method -ADC level and tumor volume pretreatment <br /><br>-Change ADC level and gross tumor volume during therapy <br /><br>-The optimal time point for MRI scanning during treatment in order to predict treatment outcome<br>