EFFECTIVENESS OF CONVENTIONAL MRI AND DIFFUSION TENSOR IMAGING TO PROGNOSTICATE OUTCOME OF SURGICALLY TREATED CERVICAL MYELOPATHY PATIENTS
Not Applicable
Completed
- Conditions
- Health Condition 1: M500- Cervical disc disorder with myelopathy
- Registration Number
- CTRI/2021/03/032148
- Lead Sponsor
- INK institute of neurosciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
• >18 years.
•Elective cervical surgery for cervical compressive myelopathy (due to spondylosis or ossified posterior longitudinal ligament) with evidence of cord compression in radiological imaging with correlating clinical features of myelopathy or myeloradiculopathy.
Exclusion Criteria
•Patients scheduled for revision procedures.
•Patients undergoing surgical procedures for traumatic, neoplastic, or infectious indications.
•Patients in whom MRI is contraindicated.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To find the predictive values of MRI parameters like the compression ratio (CR) , transverse area (TA), and signal intensity ratio (SIR) and DTI parameters like - apparent diffusion coef�cient (ADC) and fractional anisotropy (FA) Relative anisotropy (RA), Volume ratio (VR) on clinical improvement (JOA score)in Degenerative cervical myelopathy of the spinal cord. The final JOA score will be used calculate clinical improvement.Timepoint: JOA score will be calculated preoperative, 1,2 and 3 months postoperative
- Secondary Outcome Measures
Name Time Method 1.Clinical outcome measure using difference in Nurick scale. <br/ ><br>2.To calculate change in signal intensity ratio (SIR), apparent diffusion coef�cient (ADC) and fractional anisotropy (FA) Relative anisotropy (RA), Volume ratio (VR) pre and post operatively and check for correlation with clinical improvement (JOA score). <br/ ><br>3.Difference of Neck Disability Index questionnaire score and a visual analogue scale for pain.Timepoint: preoperative, 1 , 2 , 3 months post operative