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Clinical Trials/NCT05414682
NCT05414682
Completed
Not Applicable

Brain Healthy Soul Food Diet Intervention Among Older African Americans (Aim 2-3)

University of Kansas Medical Center1 site in 1 country29 target enrollmentAugust 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiovascular Diseases
Sponsor
University of Kansas Medical Center
Enrollment
29
Locations
1
Primary Endpoint
Feasibility: Retention Rate
Status
Completed
Last Updated
6 months ago

Overview

Brief Summary

The primary goal of this project is to evaluate feasibility and acceptability of the MIND+SOUL diet and its implementation. Secondary goals of this project are to evaluate cardiovascular risk profile, nutritional health status, and cognition in relation to the MIND+SOUL diet intervention.

Detailed Description

This is a single arm trial designed to pilot test an adapted brain healthy diet intervention among older AA (n=30). Specifically, this study aims to evaluate the feasibility and acceptability of the brain healthy soul food diet intervention. As secondary outcomes, this study aims to assess body composition, cardiovascular risk, nutritional health status, and changes in cognition among older AA to form the basis of estimating power and sample size for a future full-scale randomized controlled clinical trial.

Registry
clinicaltrials.gov
Start Date
August 1, 2022
End Date
November 1, 2023
Last Updated
6 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Identify as African American or Black
  • Age 55 and older
  • English Proficient
  • 1 or more of the following CVD risk factors (high blood pressure, high cholesterol, overweight/obesity with a BMI of 25 or more)
  • Cognitively Normal with an AD8 \<2 (normal cognition)

Exclusion Criteria

  • No CVD risk factors
  • AD8 equal to or greater than 2
  • Existing diet plan prescribed by a clinician
  • Non menopausal (because of DXA scan)
  • No internet connection
  • Uncontrolled hypertension, by history, or as indicated by supine systolic blood pressure \>165 mmHg or diastolic blood pressure \>95 mmHg at the baseline visit. If an initial blood pressure reading is higher than this, an additional attempt (at this visit or on another day) could be used before excluding a patient for uncontrolled hypertension
  • Neurological diseases that impact cognition
  • Other medical conditions likely to be negatively impacted by a diet change or that could confound the study data
  • Unable or unwilling to provide written consent
  • PI determination that study is unsafe or unsuitable

Outcomes

Primary Outcomes

Feasibility: Retention Rate

Time Frame: 12 weeks

Feasibility will be assessed by retention rate. This will be calculated as the percentage of participants who complete all aspects of the intervention including cooking classes and coach directed dietary call support.

Secondary Outcomes

  • Body Mass Index(Assessed at baseline and 12 weeks; 12-week data reported)
  • Total Fat Mass(Assessed at baseline and 12 weeks; 12-week data reported)
  • Android Fat Mass(Assessed at baseline and 12 weeks; 12-week data reported)
  • Waist Circumference(Assessed at baseline and 12 weeks; 12-week data reported)
  • Systolic Blood Pressure(All cardiovascular risk prolife assessments will be collected at baseline and at the 12-week mark.)
  • Total Cholesterol(All cardiovascular risk prolife assessments will be collected at baseline and at the 12-week mark.)
  • Skin Carotenoid Score (Veggie Meter) Skin Carotenoid Score (Veggie Meter) Skin Carotenoid Score (Veggie Meter)(Self-reported dietary intake was assessed at baseline and at the 12-week follow-up.)
  • Self-Reported Fruit and Vegetable Intake (NHANES Dietary Screener)(Self-reported dietary intake was assessed at baseline and at the 12-week follow-up)
  • Cognitive Function(Cognitive function was assessed at baseline and again at 12 weeks. The data table reports the outcome value from the 12-week time point.)
  • Feasibility: Reasons for Refusal(Reasons for refusal were supposed to be tracked throughout the recruitment period, which lasted approximately three months, but were not tracked.)
  • Satisfaction - Visual Analog Scale(Satisfaction assessment will be conducted at the 12-week mark.)
  • Acceptability(Acceptability assessment will be conducted at the 12-week mark.)

Study Sites (1)

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