Does thermotherapy lead to decreased analgesic requirement in patients with osteoarthritis of knee managed non-surgically.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 312
- 试验地点
- 1
- 主要终点
- - WOMAC score
研究概览
简要总结
Osteoarthritis knee constitutes one the most common ailments presenting to orthopaedic OPD and society in general. NSAIDs constitute the mainstay of treatment and can relieve pain effectively, but they also have side effects. The risk of side effects depends on age and comorbidity patient may have. People who already have other illnesses, like renal,hepatic and gastrointestinal diseases, may not tolerate them well. Drug interaction is also a challenge in using NSAIDs. Thermotherapy(cold and heat) has shown effectiveness in relieving pain and discomfort of knee osteoarthritis. In contrast to NSAIDs, no adverse effects of the thermotherapy were reported in the literature. No consideration of drug interaction and no optimization in view of comorbidity is needed.However standardized and scientific study to prove this fact is lacking.A well designed two arm study comparaing NSAIDs and thermotherapy group will be helpful in giving more insight on this issue and making thermotherapy a standard treatment modality of degenerative knee disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- Investigator Blinded
入排标准
- 年龄范围
- 40.00 Year(s) 至 70.00 Year(s)(—)
- 性别
- All
入选标准
- •The patient with Knee pain of at least 6 months duration.
- •THe patients having Primary Osteoarthritis of knee(Kellgren Lawrence Grade 1,2,3,4) -The patients with Weight bearing X-rays of the knee showing OA knee.
- •Full ambulant patients.
- •Patients opting for conservative management of OA knee.
排除标准
- •The Patients with Infective pathology.
- •The patients having Focal chondral defects.
- •The patients with Post traumatic Osteoarthritis.
- •Those who are having Degenerative subluxation of the Knee joint.
- •Patient shaving Ligamentous instability.
- •Inflammatory arthritis.
结局指标
主要结局
- WOMAC score
时间窗: 3,6,9 weeks
- IKDC score
时间窗: 3,6,9 weeks
次要结局
- VAS score(12 months)
研究者
Dr Abhishek Kumar Mishra
AIIMS,Rajkot
