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临床试验/NCT07197281
NCT07197281尚未招募不适用

Correlation Between Perfusion Index Ratio and End Diastolic Velocity Ratio After Supraclavicular Brachial Plexus Block as an Early Predictor of Successful Block in Superficialization Surgery of the Upper Limb

Assiut University0 个研究点目标入组 50 人开始时间: 2026年5月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
50
主要终点
Change in Perfusion Index ratio

研究概览

简要总结

This is a prospective observational study investigating the correlation between Perfusion Index (PI) ratio and End Diastolic Velocity (EDV) ratio as early predictors of successful supraclavicular brachial plexus block (SCBPB) in patients undergoing superficialization surgery of the upper limb.

详细描述

Regional anesthesia is fundamental for upper limb surgeries, with SCBPB providing dense anesthesia. However, early confirmation of successful block performance remains challenging. Traditional clinical methods (sensory/motor testing) are subjective and delayed. This study proposes using objective, noninvasive indices - PI (evaluated via pulse oximetry) and EDV (measured by Doppler ultrasound) - to determine their accuracy in detecting sympathetic blockade shortly after SCBPB. Early and reliable detection of block success is particularly important in superficialization surgeries such as arteriovenous fistula (AVF) superficialization in patients with compromised vascular status. The results are expected to enhance anesthesia practice by providing quantitative, reproducible, and rapid assessment tools.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults aged 18-65 years
  • Both genders
  • ASA II-VI classification
  • Undergoing elective upper limb superficialization surgery (e.g., AVF superficialization)
  • Provided written informed consent

排除标准

  • Patient refusal
  • Coagulopathy or bleeding disorders
  • Local infection at injection site
  • Allergy to local anesthetics
  • Use of vasopressors or beta-blockers
  • Severe peripheral vascular disease
  • Morbid obesity (BMI > 35)
  • Severe neurological or psychiatric disorders

结局指标

主要结局

Change in Perfusion Index ratio

时间窗: 15 minutes

Change in Perfusion Index ratio at 15 minutes after supraclavicular brachial plexus block in predicting successful block

Change in End Diastolic Velocity ratio

时间窗: 15 minutes

Change in End Diastolic Velocity ratio at 15 minutes after supraclavicular brachial plexus block in predicting successful block

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohamed Abubakr Ali

resident at the Anesthesia, Intensive Care, and Pain Management department

Assiut University

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