Microbiologic Profile And Factors Associated To Intensive Care Admission And Mortality In Patients With Emphysematous Pyelonephritis: A 10-Year Experience In A Tertiary Care Center
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 65
- 试验地点
- 1
- 主要终点
- Number of patients with admission to Intensive care unit
研究概览
简要总结
Emphysematous pyelonephritis is a lifethreatening necrotizing infection of the kidney characterized by accumulation of gas in the renal parenchyma and within the surrounding tissues. The aim of the study is to report the outcome of the management of this condition at the investigators institution and to determine the microbiological characteristics, antibiotic resistance patterns, and to analyze factors predicting mortality and intensive care unit admission.
详细描述
The investigators are planning to perform a retrospective study analyzing cases of emphysematous pyelonephritis from a single tertiary care institution in the north of Mexico in the period of 2011-2021. The diagnosis of emphysematous pyelonephritis is confirmed by computed tomography. Demographic, clinical, biochemical, therapeutic management, and outcomes will be collected. Variables will be analyzed to determine factors associated with admission to intensive care unit and mortality. Urine cultures will be analyzed and drug resistance profile will be determined using microdilution plate. Clinical and demographic characteristics will be analyzed using Chi square test for categorical variables, and T-test for numerical variables. Statistical significance is set at p<0.05. Statistical analysis will be performed with the SPSS software version 20.0.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Emphysematous pyelonephritis confirmed with computed tomography
- •Systemic inflammatory response
- •Urinary tract infection symptoms
- •Complete medical records
- •Both genders included
- •>18 years old
排除标准
- •Other infectious causes
- •Asymptomatic bacteriuria
- •Incomplete medical records
- •Endourologic procedure 3 months before recruitment
结局指标
主要结局
Number of patients with admission to Intensive care unit
时间窗: 10 years
Patients with criteria to admit to intensive care unit
Rate of mortality
时间窗: 10 years
Death cases during hospitalization
次要结局
- Antibiotic susceptibility(10 years)
研究者
Adrián Gutiérrez González
Head of Urology Department
Hospital Universitario Dr. Jose E. Gonzalez