Efficacy and safety of NSAIDs spray for pain relieving in patients with acute gouty arthritis : a randomized control trial

Phase 4

Recruiting

• Conditions: change of pain-VAS score in acute gout flare between 2 arms; Acute gout flare, topical NSAIDs, NSAIDs spray, gout

• Registration Number: TCTR20230208012
• Lead Sponsor: avamindradhiraj University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-02-08
• Study Completion: 2024-01-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 112

Inclusion Criteria

1.Patient age 18 year or more
2.Patient classified having gout with ACR/EULAR classification criteria 2015 present with Acute arthritis

Exclusion Criteria

Participant can not communicate or follow command : confusion, coma
Contraindications for colchicine, topical NSAIDs
Concomitant with other diagnosis : RA, PSA, septic arthritis, CPPD
ICU patient : post cardiac arrest, septic shock, acute respiratory failure on ventilator
NSAIDs, steroid, colchicine before start treatment
Initial eGFR below 30 ml/min/1.73m2
Acute gout flare duration > 5 day

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain 2 day after treatment Visual analogue scale

Secondary Outcome Measures

Name	Time	Method
Safety 7 day Patient report, Creatinine, AST, ALT, ALT,Safety 2 day Patient report