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Clinical Trials/NCT03690817
NCT03690817
Unknown
N/A

The Link Between Hearing Loss, Vestibular Loss and Cognitive Performance: Cross-sectional Data in Patients With Bilateral Vestibulopathy

University Hospital, Antwerp1 site in 1 country70 target enrollmentSeptember 1, 2017

Overview

Phase
N/A
Intervention
Not specified
Conditions
Vestibular Disorder
Sponsor
University Hospital, Antwerp
Enrollment
70
Locations
1
Primary Endpoint
The Repeatable Battery for the Assessment of Neuropsychological Status for Hearing Impaired Individuals (RBANS-H): total score
Last Updated
7 years ago

Overview

Brief Summary

Hearing loss is an established independent risk factor for dementia. Likewise, recent research demonstrated cognitive deficits in subjects with vestibular loss. However, in these studies data have not been adjusted for the hearing status of the enrolled study subjects. As hearing loss prevalence is high in patients with vestibular loss, this could be a major confounder. Therefore, in this study the investigators investigate cognition in patients with bilateral vestibulopathy with and without hearing loss. The investigators adjust data for the hearing status of the patients to explore the link between hearing loss, vestibular loss and cognition.

Registry
clinicaltrials.gov
Start Date
September 1, 2017
End Date
July 1, 2019
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ethisch Comité, UZA

Principal Investigator

University Hospital, Antwerp

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

The Repeatable Battery for the Assessment of Neuropsychological Status for Hearing Impaired Individuals (RBANS-H): total score

Time Frame: 2 years

General cognitive assessment, cfr. Claes et al 2016. The total-score is standardized with a mean of 100 and a standard deviation of 15. The higher the total score, the better the cognition of the participant.

Virtual Morris Water Maze performance

Time Frame: 2 years

Spatial cognition assessment, cfr. Hamilton. Path length and latency are recorded, the higher the worse the spatial cognition of the participant.

Secondary Outcomes

  • The Repeatable Battery for the Assessment of Neuropsychological Status for Hearing Impaired Individuals (RBANS-H): index scores(2 years)

Study Sites (1)

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