Effect of Diverse Training Programs on Prevention of Sarcopenia in Postmenopausal Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Skeletal muscle index
研究概览
简要总结
This study explored preventive measures for sarcopenia in apparently healthy postmenopausal women. The investigators implemented a short Nordic walking intervention, Bungy Pumo exercises and strength training, and conducted a 3-month training program as an intervention method. The subjects divided into the NW (Nordic walking) test group, the ST (Strength Training) test group, BP (Bungy Pump exercises) test group and the control group, which engaged in regular daily activities without any additional physical exercise. The collected experimental data then processed and analyzed to objectively assess the benefits and limitations of different interventions.
详细描述
The tests were conducted twice (before and after the training period). Each test lasted two days and will be preceded by a 7-day measurement of physical activity using sport testers. On the first day, blood tests, microbiota, body composition and a preliminary analysis of diet diaries were performed. On the second day, physical fitness tests were carried out in the Physical Exercise Laboratory of the AWFiS in Gdańsk. Biological material (blood serum and feces) was frozen for testing by the project contractors in the Laboratory of Genetics in Sports of the AWFiS. The subjects were required to keep a diet diary in which they recorded meals during the 3 days preceding the blood and intestinal microbiota test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Postmenopausal women over 60 years old (i.e. more than 12 months since their last menstrual cycle).
- •There were no contraindications to exercise after case reports and initial diagnosis.
- •Informed consent must be signed, agreeing to participate in research and physical exercise programs.
排除标准
- •Uncontrolled high blood pressure. Coronary artery disease. Rheumatoid arthritis. Type 2 diabetes. Respiratory diseases and lung diseases. Are taking or have used antibiotics and/or antifungal therapy in the past 4 weeks.
- •Unwillingness to stick to a prescribed schedule.
研究组 & 干预措施
Nordic walking
Training is about 60 minutes each time, 3 times a week, each interval of 1 or 2 days, a total of 12 weeks. The primary focus is on utilizing a specialized pole for engaging in cross-country walking. This regimen entails approximately 10 minutes of warm-up exercises, followed by around 40 minutes of brisk walking, and concluding with a period of relaxation stretching lasting between 5 to 8 minutes.
干预措施: Nordic walking (Behavioral)
Daily life
The individuals engaged in routine daily tasks, while being advised against incorporating any supplementary physical exertion.
Strength training
Strength training was conducted in the gym with progressively increasing resistance from 65% to 75% of the maximum weight (one-repetition maximum (1-RM)). Participants performed 10-13 repetitions of the exercise in one serie. The training was carried out in station form and consisted of 10-13 exercises. There were rest intervals of 60-90 seconds between exercises. As intended, the training was comprehensive, i.e. it affected the muscles of the arms, legs, torso, abdomen and chest.
干预措施: Strength training (Behavioral)
Bungy Pump Exercises
The training lasts approximately 60 minutes each time, 3 times a week, for a period of 12 weeks. The main emphasis is placed on the use of a specialist Bungy Pump pole. Bungy Pump training allows participants to combine aerobic and strength training. Bungy Pump poles contain a built-in shock absorber (RSA) in the form of an elastic band. The additional resistance generated by the stretched band increases the overall intensity of the exercise and increases calorie consumption. The program classes will include approximately 10 minutes of warm-up exercises, followed by approximately 40 minutes of brisk walking, and at the end a period of relaxation stretching lasting from 5 to 8 minutes.
干预措施: Bungy Pump Exercises (Behavioral)
结局指标
主要结局
Skeletal muscle index
时间窗: From enrollment to the end of treatment at 2 weeks
SMI in InBody is calculated as follows: SMI= sum of segmental muscle mass (two arms and two legs) ÷ height 2
Gait Speed
时间窗: From enrollment to the end of treatment at 2 weeks
In order to harmonize the pace measurement method, the 2019 Asian Sarcopenia Working Group recommends the time it takes to walk 6 meters at a normal pace from moving as a measure of average pace. The test is carried out in an inspection room that is more than 8 meters long. Crutches that participants normally use can also be used. The start and end of the 6-meter distance are clearly marked. Subjects stand with their toes touching the starting line, and after being instructed to move forward at their usual speed, subjects start walking, inspectors start timing, and when subjects fully cross the 6-meter mark with one foot, inspectors stop timing. The test is performed twice, recording the shortest time (in seconds) required to complete each distance. The smaller the value, the faster the walking speed, the better the physical ability.
Hand Strength
时间窗: From enrollment to the end of treatment at 2 weeks
HS was measured to estimate muscle strength and was performed with a hand dynamometer (SAEHAN Digital Hand Dynamometer, SAEHAN, Changwon, Korea). During the HS test, participants had to hold the dynamometer in their hand with the arm stretched parallel to the body while being instructed to stand upright. This measure was performed three times on the dominant hand with a rest interval of 1 min between measurements; finally, the best performance was used as the maximum peak (PK) of HS (in kg). The statistical analysis also included mean peak (mean PK).The higher the grip strength value, the greater the muscle strength, the better the physical ability.
Skeletal Muscle Mass
时间窗: From enrollment to the end of treatment at 2 weeks
Using the Octupole Bioimpedance InBody 720 analyzer (Biospace, Seoul, Korea), participants wore light clothing and no shoes.The higher the number, the more muscle the human body has.The ideal skeletal muscle content for men is 47% of standard body weight and 42% of standard body weight for women. A 10% move up or down is considered normal.
次要结局
- Right Arm Lean Mass(From enrollment to the end of treatment at 2 weeks)
- Left Arm Lean Mass(From enrollment to the end of treatment at 2 weeks)
- Trunk Lean Mass(From enrollment to the end of treatment at 2 weeks)
- Right Leg Lean Mass(From enrollment to the end of treatment at 2 weeks)
- Left Leg Lean Mass(From enrollment to the end of treatment at 2 weeks)
- Skeletal Lean Mass(From enrollment to the end of treatment at 2 weeks)
- PEAK AWY(From enrollment to the end of treatment at 2 weeks)
- PEAK TWD(From enrollment to the end of treatment at 2 weeks)
- Arm Circumference(From enrollment to the end of treatment at 2 weeks)
- ChairStand(From enrollment to the end of treatment at 2 weeks)
- ArmCurl(From enrollment to the end of treatment at 2 weeks)
- TUG(From enrollment to the end of treatment at 2 weeks)
- TandemBalance(From enrollment to the end of treatment at 2 weeks)
- Muscle Strength Indices(From enrollment to the end of treatment at 2 weeks)
- Myostatin(From enrollment to the end of treatment at 3 months)
- Irisin(From enrollment to the end of treatment at 3 months.)
- BDNF(From enrollment to the end of treatment at 3 months.)