Effects of Different Attentional Focus During Walking on Prefrontal Cortical Activation in Older Adults and Patients With Parkinson's Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 2
- 主要终点
- Effects of oxyhemoglobin variations on hemodynamic response in prefrontal cortex
研究概览
简要总结
Attention may influence the motor performance and frontal activity. This study will examine the effect of different attentional focus: internal, external and divided attention (dual task) on prefrontal cortical activation (fNIRS) and on gait performance. Thirty older adults and thirty PD will participate in this study.
详细描述
The subjects will be guided to walk at a normal pace while maintaining the required attentional focus. Subjects will walk on 20 m four times in each of the four different focus conditions :
- no instructions about the attentional focus
- internal focus on their feet movements,
- external focus on two lines drawn on the floor,
- divided attention (walking while performing an arithmetic task).
A fNIRS system will be used for the prefrontal cortex activation evaluation and FeetMe soles for gait analyses.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •For 2 groups :
- •Man or woman 60-85 years old
- •Informed consent obtained
- •Group Parkinson : clinical diagnosis of idiopathic Parkinson's Disease, according to the UK Brain Bank criteria.
排除标准
- •For 2 groups :
- •Assisted walker
- •Neurological (other than those resulting from Parkinson's disease), cardiologic, rheumatologic disorders
- •Disorders affecting gait.
- •Montreal Cognitive Assessment (MOCA) <
- •Concomitant medication likely to interfere with the results.
- •Group Parkinson:
- •Hoehn et Yahr > III
结局指标
主要结局
Effects of oxyhemoglobin variations on hemodynamic response in prefrontal cortex
时间窗: Baseline
Oxyhemoglobin variations in prefrontal cortex will be measured with a fNIRS system, on a 20 meters distance.
Effects of deoxyhemoglobin variations on hemodynamic response in prefrontal cortex
时间窗: Baseline
Deoxyhemoglobin variations in prefrontal cortex will be measured with a fNIRS system
次要结局
- Effects of speed on gait.(baseline)
- Effects of stride length on gait.(baseline)
- Effects of cadence on gait.(baseline)
- Effects of double support time on gait.(baseline)