Skip to main content
Clinical Trials/NCT05073874
NCT05073874
Completed
Not Applicable

Effects of Different Attentional Focus During Walking on Prefrontal Cortical Activation in Older Adults and Patients With Parkinson's Disease

Centre Hospitalier Régional d'Orléans1 site in 1 country45 target enrollmentDecember 8, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Parkinson Disease
Sponsor
Centre Hospitalier Régional d'Orléans
Enrollment
45
Locations
1
Primary Endpoint
Effects of oxyhemoglobin variations on hemodynamic response in prefrontal cortex
Status
Completed
Last Updated
last year

Overview

Brief Summary

Attention may influence the motor performance and frontal activity. This study will examine the effect of different attentional focus: internal, external and divided attention (dual task) on prefrontal cortical activation (fNIRS) and on gait performance. Thirty older adults and thirty PD will participate in this study.

Detailed Description

The subjects will be guided to walk at a normal pace while maintaining the required attentional focus. Subjects will walk on 20 m four times in each of the four different focus conditions : 1. no instructions about the attentional focus 2. internal focus on their feet movements, 3. external focus on two lines drawn on the floor, 4. divided attention (walking while performing an arithmetic task). A fNIRS system will be used for the prefrontal cortex activation evaluation and FeetMe soles for gait analyses.

Registry
clinicaltrials.gov
Start Date
December 8, 2021
End Date
May 8, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • For 2 groups :
  • Man or woman 60-85 years old
  • Informed consent obtained
  • Group Parkinson : clinical diagnosis of idiopathic Parkinson's Disease, according to the UK Brain Bank criteria.

Exclusion Criteria

  • For 2 groups :
  • Assisted walker
  • Neurological (other than those resulting from Parkinson's disease), cardiologic, rheumatologic disorders
  • Disorders affecting gait.
  • Montreal Cognitive Assessment (MOCA) \<
  • Concomitant medication likely to interfere with the results.
  • Group Parkinson:
  • Hoehn et Yahr \> III

Outcomes

Primary Outcomes

Effects of oxyhemoglobin variations on hemodynamic response in prefrontal cortex

Time Frame: Baseline

Oxyhemoglobin variations in prefrontal cortex will be measured with a fNIRS system, on a 20 meters distance.

Effects of deoxyhemoglobin variations on hemodynamic response in prefrontal cortex

Time Frame: Baseline

Deoxyhemoglobin variations in prefrontal cortex will be measured with a fNIRS system

Secondary Outcomes

  • Effects of speed on gait.(baseline)
  • Effects of stride length on gait.(baseline)
  • Effects of cadence on gait.(baseline)
  • Effects of double support time on gait.(baseline)

Study Sites (1)

Loading locations...

Similar Trials