Effect of local Dexmedetomidine on postoperative pain in perianal surgeries

Phase 2

Recruiting

• Conditions: Disease of anus.; Disease of anus and rectum, unspecified; K62.9

• Registration Number: IRCT20100920004780N11
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Class I and II ASA candidate for perianal surgery (fissures and hemorrhoids)

Exclusion Criteria

Advanced diabetes which leads to neuropathy
Neuromuscular diseases
Psychological and neurological diseases
Drug addiction
Use of analgesics or NSAIDs within the last 24 hours
Pregnancy
Body Mass Index is more than 23
Preoperative hearth rate is less than 45
Second or third-degree AV block
Use of antihypertensive drugs including methyldopa, clonidine and other alpha 2 adrenergic agonists

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain intensity. Timepoint: 1,3,6,12 and 24 hours after operation. Method of measurement: Using Visual Analogue Scale and verbal assessment on a scale of 1 to 10.;Nausea. Timepoint: 1,3,6,12 and 24 hours after operation. Method of measurement: Clinical observations.;Vomiting. Timepoint: 1,3,6,12 and 24 hours after operation. Method of measurement: Clinical observations.;Vital signs including blood pressure and heart rate. Timepoint: Up to 24 hours after surgery. Method of measurement: Patient monitoring devices.