Does duroplasty improve outcomes after spinal cord injury?
Not Applicable
- Conditions
- Traumatic Spinal Cord Injury (TSCI)Nervous System DiseasesInjury of nerves and spinal cord at neck level
- Registration Number
- ISRCTN25573423
- Lead Sponsor
- St George's, University of London
- Brief Summary
2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/37550727/ (added 09/08/2023)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 222
Inclusion Criteria
1. Age =16 years
2. Severe cervical (C2 – T1) traumatic spinal cord injury (AIS grade A–C)
3. Deemed to require and be suitable for surgery that includes laminectomy by local surgeon
4. Surgery within 72 h of traumatic spinal cord injury (TSCI)
5. Able to provide informed consent or proxy consent or consent/declaration provided by consultee, nearest relative/guardian/welfare attorney
Exclusion Criteria
1. Dural tear due to traumatic spinal cord injury (TSCI)
2. Life-limiting or rehabilitation-restricting co-morbidities
3. Thoracic or lumbar traumatic spinal cord injury
4. Other central nervous system disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Functional impairment measured using the American Spinal Injury Association Impairment Scale total limb motor score at baseline and 6 months
- Secondary Outcome Measures
Name Time Method