Studies on Permeability of the Blood-Brain-Barrier for Escitaloprame related to various Genotypes of the ABCB1-Gene: Effects on Sleep and Motoric Learning - Escitaloprame, sleep, blood-brain-barrier
- Conditions
- Effects on sleep electroencephalogram and motoric learning in healthy volunteers related to the permeability of the blood-brain-barrier related to genotypes of the ABCB 1 gene
- Registration Number
- EUCTR2006-001491-21-DE
- Lead Sponsor
- Max Planck Institute of Psychiatry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- Male
- Target Recruitment
- 58
healthy male volunteers, 20 to 30, or 50 to 60 years old,
genotype A/A or B/B of the ABCB1 gene,
capable to perform all tests and examinations,
capable to understand the aims of the study,
written informed consent.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
participation in another trial during the last month,
psychiatric disorders, present or during life time,
sleep disorders present or during the last 3 months,
night work or transmeridian flight during the last 3 months,
serious somatic disorders,
intake of drugs during more than 2 days during the last 3 months,
any drug intake during the last month,
smoker,
abuse of alcohol,
more than 2 cups coffee per day,
recreational drugs during the last 4 months.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method