The effects of critical illness on small intestinal transit and nutrient absorptio

Not Applicable

Completed

• Conditions: critically ill patients; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12608000579392
• Lead Sponsor: Adam Deane

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-11-19
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

critically ill patients
sedated and mechanically ventilated
suitable for, or receiving small intestinal nutrition

Exclusion Criteria

Pregnancy
Any contraindication to placement of a post-pyloric feeding tube
contraindication to enteral feeding
Previous surgery on the duodenum/small intestine
Any gastrointestinal surgery during their current hospital admission
Patients receiving erythromycin at an antimicrobial dose

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
small intestinal transit time using a labelled meal and scintigraphic camera[4-6 hours];nutrient absorption using plasma concentrations of 3-OMG[4-6 hours];association between transit time and nutrient absorption using statistical analysis[4-6 hours]

Secondary Outcome Measures

Name	Time	Method
pre-defined subgroup of patients receiving opiate and not receiving opiate and compare transit time/nutrient absorption[2-8 hours]