Dose-Ranging Study in Patients With Chronic Obstructive Pulmonary Disease (COPD)
- Conditions
- COPD
- Registration Number
- NCT00098228
- Lead Sponsor
- Novartis Pharmaceuticals
- Brief Summary
The trial is designed to identify an appropriate dose of QAB149 for delivery via a multiple dose inhaler for use in the COPD Phase III program.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 686
- Diagnosis of COPD
- Age 40-75 years
- Smoking history
- Other serious disease
- Allergy to QAB149
- Respiratory tract infection
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Pulmonary function measured between 22 and 24 hours after dosing on Day 1
- Secondary Outcome Measures
Name Time Method Safety measurements Pulmonary function measured on days 1 and 7 at various intervals after dosing
Trial Locations
- Locations (54)
Allergy Research Foundation , Inc
🇺🇸Los Angeles, California, United States
David Geffin UCLA School of Medicine
🇺🇸Los Angeles, California, United States
UAB Pulmonary Research
🇺🇸Birmingham, Alabama, United States
Diagnostic & Medical Clinic
🇺🇸Mobile, Alabama, United States
Upstate Pharmaceutical Research
🇺🇸Simpsonville, South Carolina, United States
Central Texas Health Research
🇺🇸New Baunfels, Texas, United States
Asthma & Allergy Res. Associates
🇺🇸Dallas, Texas, United States
Trinity Clinic Office of Research Admin.
🇺🇸Tyler, Texas, United States
Madrona Medical Group
🇺🇸Bellingham, Washington, United States
The University of South Alabama Medical Center
🇺🇸Mobile, Alabama, United States
Allergy Associates Research Center
🇺🇸Portland, Oregon, United States
Pulmonary Consultants, PLLC
🇺🇸Tacoma, Washington, United States
Healthcare Research Consultants Inc.
🇺🇸Tulsa, Oklahoma, United States
River Road Medical Group
🇺🇸Eugene, Oregon, United States
Cloverdale Research Facility
🇺🇸Winston Salem, North Carolina, United States
Low Country Lung and Critical Care
🇺🇸Charleston, South Carolina, United States
Sylvana Research
🇺🇸San Antonio, Texas, United States
Pulmonary Associates
🇺🇸Phoenix, Arizona, United States
Southern California Research
🇺🇸Mission Viejo, California, United States
USC Rancho Amigos Medical Center
🇺🇸Downey, California, United States
California Allergy & Asthma Medical Group
🇺🇸Palmdale, California, United States
Allergy Associates Medical Group, Inc
🇺🇸San Diego, California, United States
Allergy & Asthma Associates of Santa Clara Research Center
🇺🇸San Jose, California, United States
Rocky Mountain Center for Clinical Research
🇺🇸Wheat Ridge, Colorado, United States
University of Miami School of Medicine
🇺🇸Miami, Florida, United States
Physician's Research Center
🇺🇸Hartford, Connecticut, United States
Crescent Clinical Research
🇺🇸Pensacola, Florida, United States
Bensch Clinical Research Associates
🇺🇸Stockton, California, United States
USF Asthma, Allergy & Immunology, Clinical Research Unit
🇺🇸Tampa, Florida, United States
Radiant Research - Atlanta West
🇺🇸Austell, Georgia, United States
Cordova Medical Center
🇺🇸Pensacola, Florida, United States
University Medical Associates, LLP
🇺🇸Augusta, Georgia, United States
Sneeze, Wheeze & Itch Associates, LLC
🇺🇸Normal, Illinois, United States
New Orleans Center for Clinical Research
🇺🇸New Orleans, Louisiana, United States
St. Elizabeth's Medical Center
🇺🇸Brighton, Massachusetts, United States
Center for Clinical Research
🇺🇸Tauton, Massachusetts, United States
Asthma and Allergy Center of Chicago S.C.
🇺🇸River Forest, Illinois, United States
Pulmonary Respiratory Institute of Southeast Michigan
🇺🇸Livonia, Michigan, United States
ClinSite, Inc.
🇺🇸Ann Arbor, Michigan, United States
University of Michigan Health System
🇺🇸Ann Arbor, Michigan, United States
The Clinical Research Center
🇺🇸St. Louis, Missouri, United States
Clinical Research Institute
🇺🇸Minneapolis, Minnesota, United States
Creigton University
🇺🇸Omaha, Nebraska, United States
Univ. of Nebraska Medical Center--Pulmonary Research
🇺🇸Omaha, Nebraska, United States
New England Clinical Research
🇺🇸North Dartmouth, New Hampshire, United States
Minnesota Lung Center
🇺🇸Minneapolis, Minnesota, United States
AAIR Reseach Center
🇺🇸Rochester, New York, United States
University of Noth Carolina--Pulmonary Division
🇺🇸Chapel Hill, North Carolina, United States
Princeton Center for Clinical Research
🇺🇸Skillman, New Jersey, United States
Pulmonary & Allergy Associates
🇺🇸Springfield, New Jersey, United States
Oklahoma Allergy and Asthma Clinic
🇺🇸Oklahoma City, Oklahoma, United States
North Carolina Clinical Research
🇺🇸Raleigh, North Carolina, United States
VA Medical Center
🇺🇸Oklahoma City, Oklahoma, United States
Radiant Research
🇺🇸Encinitas, California, United States