Clinical study on the same disease and different treatment of DME in different stages of visio

Phase 1

• Conditions: diabetic macular edema

• Registration Number: ITMCTR2000003935
• Lead Sponsor: ongHua Hospital, Shanghai University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

A. Have a clear history of diabetes and receive diabetes treatment.
B. It was in accordance with the diagnosis of diabetic retinopathy.
C. OCT examination showed macular edema.
D. Willing to accept vitreous injection and oral Chinese medicine treatment.
E. Male and female patients aged 18-75 years.
F. The visual acuity ranged from 0.05 to 0.8.
G. Volunteer and sign informed consent.

Exclusion Criteria

A. Pregnant or lactating women.
B. Abnormal liver function.
C. Diabetic nephropathy has renal failure (azotemia, uremia).
D. There are other serious diseases (such as malignant tumor, acute myocardial infarction, heart failure, acute stroke, serious psychosis, chronic alcoholism, etc.).
E. Patients with other eye diseases (such as glaucoma, severe cataract, non-diabetic hemorrhagic fundus disease, uveitis, retinal detachment, optic nerve disease, etc.) and those with unclear refractive stroma.
F. Patients with allergic diseases or allergic to this drug.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Best corrected visual acuity;

Secondary Outcome Measures

Name	Time	Method
The thickness of macular fovea and the degree of paracentral macular edema;Microangioma, hemorrhage, exudation, edema changes;Symptoms and signs of traditional Chinese Medicine;