Single centre study comparing results of pathologic analysis of EUS-FNA with EUS-TCB in patients with enlarged mediastinal lymph nodes.

• Conditions: lymph node enlargement; indication for diagnosis; 10025323; 10038666

• Registration Number: NL-OMON35501
• Lead Sponsor: Isala Klinieken

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

Patients with large mediastinal lymph nodes (>2cm) at location Naruke 7 or Naruke 4 Left on CT or PET-CT.
Enlarged lymph nodes on EUS more than 2cm.
Age 18 and older.
ASA classification 1 - 3
Informed consent

Exclusion Criteria

ASA classification > 3
Obstructing oral or laryngeal disease.
Severe maxillofacial deformity

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study endpoint will be the difference between EUS-FNA alone and<br /><br>EUS-FNA and EUS-TCB.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary endpoint will be the amount of adverse events seen with the<br /><br>procedure like bleeding and mediastinitis.</p><br>