Improving Weight Loss Maintenance Through Alternative Schedules of Treatment
Not Applicable
Completed
- Conditions
- Obesity
- Registration Number
- NCT02487121
- Lead Sponsor
- University of Alabama at Birmingham
- Brief Summary
This project examines the effects of differing schedules of extended care contact following weight loss treatment in order to prevent weight regain following treatment.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 108
Inclusion Criteria
- At least 21 years-old
- body mass index (BMI) = 28.0 - 45.0 kg/m2
- willing to provide informed consent and accept randomization
Exclusion Criteria
- BMI >45 kg/m2
- Illnesses requiring medical attention and/or conditions for which weight loss and moderate physical activity would be inadvisable: diabetes not under active treatment, myocardial infarction or cerebrovascular accident within the last six months; unstable angina within the past six months; congestive heart failure; cancer requiring treatment in past five years (exception: non-melanoma skin cancer); serious infectious diseases (e.g., self-reported HIV); chronic hepatitis; cirrhosis; chronic malabsorption syndrome; chronic pancreatitis; chronic lung diseases that limit physical activity; orthopedic injuries or conditions that significantly limit physical activity.
- Conditions or behaviors likely to affect the conduct of the trial: unwilling or unable to give informed consent; unable to read English at the 5th grade level; unwilling to accept random assignment; unwilling or unable to travel to attend intervention (due to distance from clinic, work schedule or other scheduling conflicts); likely to relocate out of the service area in next 18 months.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method body weight (kg) 12 months change in body weight (kg) between randomization and month-12 follow-up
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie weight regain prevention in variable interval schedules of obesity treatment?
How does variable interval behavioral intervention compare to continuous care in long-term obesity management outcomes?
Which biomarkers correlate with successful weight maintenance in NCT02487121 behavioral intervention trial?
What adverse events are associated with self-directed treatment approaches in obesity management?
Are there synergistic effects when combining variable interval schedules with pharmacological agents like GLP-1 receptor agonists in obesity treatment maintenance?