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Mechanism of upper limb spasmodic brain plasticity after cerebral infarction treated by electroacupuncture combined with low frequency rTMS

Phase 1
Conditions
pper limb spasm after cerebral infarction
Registration Number
ITMCTR2000003224
Lead Sponsor
Shenzhen Bao'an Traditional Chinese Medicine Hospital Group
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

(1) meet the above diagnostic criteria;
(2) first onset, with a course of 1-6 months, aged 35-65 years;
(3) the upper buckling model spastic paralysis, out the hierarchical II ~IV period;Improved Ashworth was used to evaluate the degree of muscle tension of hemiplegic limbs: 1 <= MAS <= 3;
(4) modified Rankin scale 1 <= MRS <= 3;
(5) the patient has clear consciousness, stable vital signs, stable condition, and can cooperate with treatment and efficacy observer;
(6) the patient and his/her family agreed to participate in the case registration study and sign the informed consent.

Exclusion Criteria

(1) persons with conscious disorders and severe aphasia;
(2) persons with secondary epilepsy, family history of epilepsy or previous abnormal mental state;
(3) patients with previous disease history of other nervous system and motor system, which affected the limb movement function of the affected side;
(4) patients with a history of brain trauma or severe heart disease (such as atrial fibrillation, valvular heart disease, etc.);
(5) patients with metal implants (such as pacemaker, coronary stent, etc.);
(6) patients who take drugs with skeletal muscle relaxation effect at the same time;
(7) patients in pregnancy or lactation period.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Fugl-mever rating scale;Modified Ashworth table;PAS25, PAS10;
Secondary Outcome Measures
NameTimeMethod
Modified Barthel index scale;MEPs;rMT;
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