eg muscles neuromuscular adaptation of subjects with spasticity before and after Botulinum Toxin Type A applicatio
Phase 1
Active, not recruiting
- Conditions
- Stroke, not specified as haemorrhage or infarctionG00-G99
- Registration Number
- RBR-2scj85
- Lead Sponsor
- aboratório de Pesquisa do Exercício, Universidade Federal do Rio Grande do Sul
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Diagnosis of ischemic or hemorrhagic stroke; incident time greater than 12 months; age equal or superior to 20 years; ability to walk with or without crutches; presence of spasticity in the ankle plantiflexor muscles.
Exclusion Criteria
Do not use BTX-A for a minimum of 6 months; not be performing physiotherapy; history of surgical procedure or use of orthopedic prosthesis; use of orthoses; cardiovascular and respiratory impairment limiting physical exertion; presence of progressive or insane neurological disease.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Muscle strength increased, verified by isokinetic dynamometry, with a variation of at least 5% in pre and post-intervention measurements.;Functional performance improvement, verified by the tests: eight-meter brisk walk, Timed Up and Go and Sit-to-Stand, with a variation of at least 5% in pre and post-intervention measurements.;Muscle architecture improvement, verified by ultrasound, with a variation of at least 5% in pre and post-intervention measurements.
- Secondary Outcome Measures
Name Time Method Flexibility Increased, verified through goniometry, with a variation of at least 5% in pre and post-intervention measurements.;Spasticity reduction, verified by the Ashworth Modified Scale, with a variation of at least 5% in the pre and post intervention measurements.